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Safety Data Sheet EN

Riluzole

CAS 1744-22-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Riluzole
Product Code
459360000; 459360010; 459360050; 459360100
Synonyms
2-Amino-6-(trifluoromethoxy)benzo[d]thiazole

Regulatory Identifiers

CAS Number
1744-22-5 Check regulations →

Identified Uses

Laboratory chemicals.

Uses advised against

No Information available

Manufacturers & Suppliers

F

Fisher Scientific UK

distributor

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

T

Thermo Fisher Scientific

distributor

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

Emergency Contacts

Emergency Contact

001-800-227-6701

Emergency Contact

+32 14 57 52 11

Emergency Contact

001-201-796-7100

Emergency Contact

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 2 H300

GHS Pictograms

GHS06 - Acute toxicity

GHS06

Hazard Statements

H300 Fatal if swallowed

Precautionary Statements

P264 Wash face, hands and any exposed skin thoroughly after handling
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
P330 Rinse mouth

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Riluzole 1744-22-5 95% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Eye contact

In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Ingestion

Do NOT induce vomiting. Call a physician or poison control center immediately.

Immediate Medical Attention

Immediate medical attention is required.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.

Unsuitable media

No information available.

Specific hazards

Thermal decomposition can lead to release of irritating gases and vapors.

Instructions

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

Firefighter Protection

Wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas.

Environmental

Should not be released into the environment. See Section 12 for additional Ecological Information.

Cleanup methods

Sweep up and shovel into suitable containers for disposal.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Do not breathe (dust, vapor, mist, gas). Do not ingest. If swallowed then seek immediate medical assistance.

Storage

Keep containers tightly closed in a dry, cool and well-ventilated place. To maintain product quality; Store under an inert atmosphere.

Hygiene

Handle in accordance with good industrial hygiene and safety practice.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure adequate ventilation, especially in confined areas. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Nitrile rubber, Neoprene, Natural rubber, PVC. Breakthrough time: See manufacturers recommendations. EU standard: EN 374. (minimum requirement)

Eyes

Wear safety glasses with side shields (or goggles) (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: Particulates filter conforming to EN 143. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Particle filtering: EN149:2001. When RPE is used a face piece Fit Test should be conducted

Skin/Body

Long sleeved clothing.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
---
Colour Intensity
---
Form
---
Odor
No information available
Odor Threshold
No data available
Ph
Not applicable
Melting Point
114 - 118 °C / 237.2 - 244.4 °F
Boiling Point
Not applicable
Flash Point
Not applicable
Freezing Point
---
Softening Point
No data available
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not applicable - Solid
Vapor Pressure
No data available
Vapor Density
Not applicable
Relative Density
---
Bulk Density
No data available
Density
No data available
Flammability
No information available
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
3.5
Solubility In Water
Insoluble
Solubility In Fat
---
Molecular Weight
234.2
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
Not applicable
Kinematic Viscosity
Not applicable
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

No information available.

Reactivity

None known, based on information available

Hazardous reactions

None under normal processing. Hazardous Polymerization No information available.

Avoid

Incompatible products. Excess heat.

Incompatible

Strong oxidizing agents.

Decomposition

Carbon monoxide (CO). Nitrogen oxides (NOx). Sulfur oxides. Hydrogen fluoride. Carbon dioxide $(\mathrm{CO}_{2})$ .

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1. Toxicity

Ecotoxicity effects Contains no substances known to be hazardous to the environment or that are not degradable in waste water treatment plants.

Contains no substances known to be hazardous to the environment or that are not degradable in waste water treatment plants.

12.2. Persistence and degradability

Persistence Persistence is unlikely.

Persistence is unlikely.

12.3. Bioaccumulative potential

Bioaccumulation is unlikely | Component | log Pow | Bioconcentration factor (BCF) | | --- | --- | --- |

Bioaccumulation is unlikely

12.3. Bioaccumulative potential

| Component | log Pow | Bioconcentration factor (BCF) | | --- | --- | --- | | Riluzole | 3.5 | No data available |

12.4. Mobility in soil

Spillage unlikely to penetrate soil Is not likely mobile in the environment due its low water solubility.

The substance is not likely mobile in the environment due to its low water solubility.

12.5. Results of PBT and vPvB assessment

No data available for assessment.

12.6. Endocrine disrupting properties

Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors

12.7. Other adverse effects

Persistent Organic Pollutant Ozone Depletion Potential This product does not contain any known or suspected substance This product does not contain any known or suspected substance
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste is classified as hazardous. Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.

Disposal

Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.

Waste Codes

Not product specific Waste Codes are not product specific, but application specific. EWC
14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2811
Shipping Name
Toxic solid, organic, n.o.s.
Transport Class
6.1
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Riluzole (CAS 1744-22-5) regulatory status: Listed in TCSI and ISHL inventories. Classified as WGK 3 (water endangering) in Germany. Identified as PFAS by EU (ECHA) and UK (HSE) authorities.

Chemical Safety Assessment Not performed

PFAS Status: Riluzole (CAS 1744-22-5) is listed as PFAS under EU (ECHA) and UK (HSE) definitions.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Riluzole known by?

Riluzole is also known as: 2-Amino-6-(trifluoromethoxy)benzo[d]thiazole

What is the hazard signal word for Riluzole?

The signal word is danger.

What is the physical form of Riluzole?

Riluzole is a solid . It has no information available odor.

What is Riluzole used for?

Laboratory chemicals.

What are the hazard statements for Riluzole?

This substance has 1 hazard statement:

  • H300: Fatal if swallowed

What is the melting point of Riluzole?

The melting point is 114 - 118 °C / 237.2 - 244.4 °F and the boiling point is Not applicable.