Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Acetonitrile
- Product Code
- 271004
Regulatory Identifiers
- CAS Number
- 75-05-8 Check regulations →
- REACH No.
- 01-2119471307-38-XXXX
Identified Uses
Laboratory chemicals, Manufacture of substances
Manufacturers & Suppliers
Sigma-Aldrich Chemie GmbH
manufacturer
Eschenstrasse 5, D-82024 TAUFKIRCHEN
+49 (0)89 6513-1130
Emergency Contacts
CHEMTREC Deutschland
0800 181 7059
CHEMTREC weltweit
+49 (0)696 43508409
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS02
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Acetonitrile EC: 200-835-2 | 75-05-8 | 100% | Yes |
First Aid Measures
Emergency procedures for chemical exposure incidents
Fresh air. If breathing stops: mouth-to-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.
Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
Rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
Immediately make victim drink water (two glasses at most). Consult a physician.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Water, Foam, Carbon dioxide (CO2), Dry powder
For this substance/mixture no limitations of extinguishing agents are given.
Combustible. Fire may cause evolution of: nitrogen oxides, Hydrogen cyanide (hydrocyanic acid). Pay attention to flashback. Vapors are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Firefighter Protection
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.
Do not let product enter drains. Risk of explosion.
Take up with liquid-absorbent material (e.g. Chemizorb®). Clean up affected area.
Materials: liquid-absorbent material (e.g. Chemizorb®)
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist. Filled under nitrogen. Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Keep container tightly closed in a dry and well-ventilated place.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Keep away from open flames, hot surfaces and sources of ignition.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Full contact: Material: butyl-rubber, Minimum layer thickness: 0,7 mm, Break through time: 480 min, Material tested: Butoject® (KCL 898). Splash contact: Material: Chloroprene, Minimum layer thickness: 0,65 mm, Break through time: 10 min, Material tested: KCL 720 Camapren®. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Flame retardant antistatic protective clothing.
Do not let product enter drains. Risk of explosion.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
The product is chemically stable under standard ambient conditions (room temperature).
Vapors may form explosive mixture with air.
Violent reactions possible with: Strong bases, strong reducing agents. Risk of explosion with: nitrates, perchlorates, perchloric acid, conc. sulfuric acid, with Heat. Risk of ignition or formation of inflammable gases or vapours with: Oxidizing agents, Nitric acid, nitrogen dioxide, with Catalyst. Generates dangerous gases or fumes in contact with: Acids
Heat, Catalyst
Strong bases, strong reducing agents, nitrates, perchlorates, perchloric acid, conc. sulfuric acid, Oxidizing agents, Nitric acid, nitrogen dioxide, Acids
In the event of fire: see section 5
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
12.1 Toxicity
12.2 Persistence and degradability
12.3 Bioaccumulative potential
12.3 Bioaccumulative potential
No bioaccumulation is to be expected (log Pow <= 4).
12.4 Mobility in soil
12.5 Results of PBT and vPvB assessment
The substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Endocrine disrupting properties
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
12.7 Other adverse effects
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
No data available
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- 1648
- Shipping Name
- ACETONITRILE
- Transport Class
- 3
- Packing Group
- II
Tunnel restriction code : (D/E)
Regulatory Information
Chemical regulations, safety assessments, and compliance status
This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for Acetonitrile?
The signal word is danger.
What is the physical form of Acetonitrile?
Acetonitrile is a clear, liquid with colorless color. It has ether-like odor.
What is Acetonitrile used for?
Laboratory chemicals, Manufacture of substances
What are the hazard statements for Acetonitrile?
This substance has 3 hazard statements:
- H225: Highly flammable liquid and vapor.
- H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
- H319: Causes serious eye irritation.
What is the melting point of Acetonitrile?
The melting point is -48 °C and the boiling point is 81 - 82 °C.