Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Acetonitrile
- Product Code
- 448390000; 448391000
- Chemical Name
- Acetonitrile
- Synonyms
- AN; Methyl cyanide; Ethanenitrile
Regulatory Identifiers
- CAS Number
- 75-05-8 Check regulations →
- EC Number
- 200-835-2 Check regulations →
- REACH No.
- 01-2119471307-38
Identified Uses
Laboratory chemicals. SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites; PC21 - Laboratory chemicals; PROC15 - Use as a laboratory reagent; ERC6a - Industrial use resulting in manufacture of another substance (use of intermediates)
Uses advised against
No Information available
Manufacturers & Suppliers
Thermo Fisher Scientific
manufacturer
Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium
Fisher Scientific UK
distributor
Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom
Fisher Scientific AG
distributor
Neuhofstrasse 11, CH 4153 Reinach
+41 (0) 56 618 41 11
Emergency Contacts
Thermo Fisher Scientific (US Info)
001-800-227-6701
Thermo Fisher Scientific (Europe Info)
+32 14 57 52 11
Thermo Fisher Scientific (US Emergency)
001-201-796-7100
Thermo Fisher Scientific (Europe Emergency)
+32 14 57 52 99
CHEMTREC
001-800-424-9300
CHEMTREC
001-703-527-3887
Tox Info Suisse
145
24hr
Tox Info Suisse
+41-44 251 51 51
Chemtrec
0800 564 402
24h
Chemtrec
+41-43 508 20 11
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS02
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Acetonitrile EC: 200-835-2 | 75-05-8 | 95% | Yes |
First Aid Measures
Emergency procedures for chemical exposure incidents
Remove to fresh air. If breathing is irregular or stopped, administer artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required.
Symptoms: Difficulty in breathing. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting.
Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required.
Do NOT induce vomiting. Call a physician or poison control center immediately.
Symptoms: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting.
Immediate Medical Attention
Immediate medical attention is required. Call a physician or poison control center immediately.
Medical Treatment
Treat symptomatically. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Water spray. CO₂, dry chemical, dry sand, alcohol-resistant foam. Water mist may be used to cool closed containers.
Do not use a solid water stream as it may scatter and spread fire.
Flammable. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Containers may explode when heated. Vapors may form explosive mixtures with air.
Thermal decomposition can lead to release of irritating gases and vapors.
Firefighter Protection
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Remove all sources of ignition. Take precautionary measures against static discharges. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Use personal protective equipment as required.
Should not be released into the environment.
Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.
Materials: inert absorbent material
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Wear personal protective equipment/face protection. Ensure adequate ventilation. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Do not get in eyes, on skin, or on clothing. Do not breathe mist/vapors/spray. Use spark-proof tools and explosion-proof equipment. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat, sparks and flame. Flammables area.
When using do not eat, drink or smoke. Provide regular cleaning of equipment, work area and clothing.
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Use explosion-proof electrical/ventilating/lighting/equipment. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source
Protective gloves. Glove material: Butyl rubber, Breakthrough time: >480 minutes, Glove thickness: 0.35 mm, EU standard: EN 374, Glove comments: As tested under EN374-3 Determination of Resistance to Permeation by Chemicals. Neoprene gloves, Breakthrough time: <60 minutes, Glove thickness: 0.45 mm, EU standard: Level 6.
Goggles (European standard - EN 166)
When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: low boiling organic solvent Type AX Brown conforming to EN371. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141
Wear appropriate protective gloves and clothing to prevent skin exposure. Inspect gloves before use. observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) gloves are suitable for the task: Chemical compatibility, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. gloves with care avoiding skin contamination.
No information available.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
Stable under normal conditions.
None known, based on information available
Hazardous polymerization does not occur. No information available.
Incompatible products. Keep away from open flames, hot surfaces and sources of ignition. Exposure to moisture.
Strong oxidizing agents. Strong acids. Reducing Agent. Bases.
Hydrogen cyanide (hydrocyanic acid). Nitrogen oxides (NOx). Carbon monoxide (CO). Carbon dioxide (CO₂).
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
The data for this section has not been processed yet.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- UN1648
- Shipping Name
- ACETONITRILE
- Transport Class
- 3
- Packing Group
- II
Regulatory Information
Chemical regulations, safety assessments, and compliance status
The data for this section has not been processed yet.
Frequently Asked Questions
Common questions about safety, handling, and properties
What other names is Acetonitrile known by?
Acetonitrile is also known as: AN; Methyl cyanide; Ethanenitrile
What is the hazard signal word for Acetonitrile?
The signal word is danger.
What is the physical form of Acetonitrile?
Acetonitrile is a liquid appearing as colorless . It has aromatic odor.
What is Acetonitrile used for?
Laboratory chemicals. SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites; PC21 - Laboratory chemicals; PROC15 - Use as a laboratory reagent; ERC6a - Industrial use resulting in manufacture of another substance (use of intermediates)
What are the hazard statements for Acetonitrile?
This substance has 3 hazard statements:
- H225: Highly flammable liquid and vapor
- H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled
- H319: Causes serious eye irritation
What is the melting point of Acetonitrile?
The melting point is -46 °C / -50.8 °F and the boiling point is 81 - 82 °C / 177.8 - 179.6 °F.