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Acetonitrile

DANGER clear, liquid SDS/MSDS
Chemical Identity

Product Identification & Regulatory Data

Official chemical identifiers, CAS numbers, and regulatory compliance information

Basic Product Information

Product Name
Acetonitrile
Product Code
271004
Chemical Name
ACETONITRIL (methylcyanide)
Synonyms
geen gegevens beschikbaar

Regulatory Identifiers

CAS Number

Chemical Abstracts Service registry number - unique identifier for chemical substances

EC Number

European Community number - used for regulatory compliance in EU/EEA

REACH Registration Number
01-2119471307-38

Registration, Evaluation, Authorisation and Restriction of Chemicals - EU regulation compliance

Uses Information

Identified Uses
Laboratory chemicals, Synthesis of substances

Overview

Acetonitrile (CAS: 75-05-8 ) is a clear, liquid color: colorless substance commonly used laboratory chemicals, synthesis of substances.

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Organize and access your chemical safety data with ease.

Safety Classification

GHS Hazard Classification & Safety Warnings

Globally Harmonized System (GHS) hazard pictograms, signal words, and safety classifications

Classification Status

Classified

Signal Word

danger (Danger)

Hazard Classifications

Flam. Liq. Category 2 H225
Acute Tox. Category 4 H302
Acute Tox. Category 4 H332
Acute Tox. Category 4 H312
Eye Irrit. Category 2A H319

GHS Hazard Pictograms & Safety Symbols

GHS02 GHS Hazard Pictogram: Flammable hazard - Fire risk materials including gases, liquids, and solids

GHS02

GHS (Globally Harmonized System) pictograms indicate specific chemical hazard categories and safety precautions

Hazard Statements

  • H225: Highly flammable liquid and vapor.
  • H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
  • H319: Causes serious eye irritation.

Precautionary Statements

  • P210: Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking.
  • P233: Keep container tightly closed.
  • P240: Ground/bond container and receiving equipment.
  • P241: Use explosion-proof electrical/ ventilating/ lighting/ equipment.
  • P242: Use only non-sparking tools.
  • P243: Take precautionary measures against static discharge.
  • P261: Avoid breathing mist or vapors.
  • P264: Wash skin thoroughly after handling.
  • P270: Do not eat, drink or smoke when using this product.
  • P271: Use only outdoors or in a well-ventilated area.
  • P280: Wear protective gloves/ eye protection/ face protection.
  • P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337 + P313: If eye irritation persists: Get medical advice/ attention.
  • P363: Wash contaminated clothing before reuse.
  • P370 + P378: In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
  • P403 + P235: Store in a well-ventilated place. Keep cool.
  • P501: Dispose of contents/ container to an approved waste disposal plant.
  • IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.
  • IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell.
Supply Chain

Manufacturers & Suppliers

Authorized suppliers, manufacturers, and distribution network information

Sigma-Aldrich Inc.

global supplier

3050 SPRUCE ST ST. LOUIS MO 63103 UNITED STATES

US

+1 314 771-5765

+1 800 325-5052

Emergency

24/7 Emergency Response

Critical emergency contact numbers for chemical spills, exposure incidents, and medical emergencies

CHEMTREC

800-424-9300

US

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

US

24 Hours/day; 7 Days/week

International

Composition

Chemical Composition & Hazardous Ingredients

Detailed component analysis, concentration ranges, and hazardous substance identification

Product Type

substance

Chemical Components & Hazardous Substances

Chemical Name CAS Number Concentration Hazardous
Acetonitrile
EC: 200-835-2
75-05-8 100% Hazardous
First Aid

Emergency First Aid Measures

Critical first aid procedures for chemical exposure incidents and medical emergencies

Inhalation Exposure

After inhalation: fresh air. If breathing stops: mouth-to-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.

Skin Contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye Contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion/Swallowing

Immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention Required

No data available

Alternatives

Related Chemical Substances & Alternative Products

Similar chemicals with comparable safety profiles and industrial applications

Section 9

Technical Specifications & Material Properties

Physical state, chemical properties, melting point, boiling point, and material characteristics

Physical State
clear, liquid
Critical Property
Physical State Data
liquid
State Under Standard Conditions
Not available
Appearance
clear, liquid Color: colorless
Colour
colorless
Colour Intensity
Not available
Form
clear, liquid
Odor
ether-like
Odor Threshold
39.8 ppm
Ph
No data available
Melting Point
-48 °C (-54 °F)
Critical Property
Boiling Point
81 - 82 °C 178 - 180 °F
Critical Property
Flash Point
2.0 °C (35.6 °F)
Critical Property
Freezing Point
Not available
Softening Point
Not available
Solidification Point
Not available
Cloud Point
Not available
Crystallisation Point
Not available
Relative Evaporation Rate
Not available
Evaporation Rate
5.8
Vapor Pressure
98.64 hPa at 20 °C (68 °F)
Vapor Density
1.42 - (Air = 1.0)
Relative Density
No data available
Bulk Density
Not available
Density
0.786 g/mL at 25 °C (77 °F)
Critical Property
Flammability
No data available
Upper Explosive Limit
16 %(V)
Lower Explosive Limit
4.4 %(V)
Explosive Limits
Not available
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
Not available
Partition Coefficient
log Pow: -0.54 at 25 °C (77 °F)
Solubility In Water
1,000 g/l at 25 °C (77 °F)completely soluble
Solubility In Fat
Not available
Molecular Weight
Not available
Voc Content
Not available
Metal Corrosion
Not available
Dynamic Viscosity
Not available
Kinematic Viscosity
Not available
Properties Status
Not available
Section 8

Exposure Controls & Personal Protective Equipment

Occupational exposure limits, engineering controls, and required safety equipment

Hand Protection

Full contact Material: butyl-rubber Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Butoject® (KCL 898). Splash contact Material: Chloroprene Minimum layer thickness: 0.65 mm Break through time: 10 min Material tested:KCL 720 Camapren®. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eye Protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory Protection

Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds. The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Skin/Body Protection

Flame retardant antistatic protective clothing.

Environmental Exposure Controls

Do not let product enter drains. Risk of explosion.

Section 14

Transportation & Shipping Information

UN numbers, shipping names, transport classes, and regulatory transport requirements

UN Number

1648

Proper Shipping Name

Acetonitrile

Transport Hazard Class

3

Packing Group

II

FAQ

Chemical Safety FAQ & Common Questions

Most frequently asked questions about safety, handling, storage, and regulatory compliance

What other names is Acetonitrile known by?

Acetonitrile is also known as: geen gegevens beschikbaar

What is the hazard signal word for Acetonitrile?

The signal word for this substance is "danger".

What is the physical form of Acetonitrile?

Acetonitrile is a clear, liquid appearing as clear, liquid color: colorless with colorless color. It has ether-like odor.

What is Acetonitrile used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Acetonitrile?

This substance has 3 hazard statements: H225: Highly flammable liquid and vapor. H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled. H319: Causes serious eye irritation.

What is the melting point of Acetonitrile?

The melting point is -48 °C (-54 °F) and the boiling point is 81 - 82 °C 178 - 180 °F.