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Safety Data Sheet EN

beta-Propiolactone

CAS 57-57-8
EC 200-340-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
beta-Propiolactone
Product Code
B23197

Regulatory Identifiers

CAS Number
57-57-8 Check regulations →
EC Number
200-340-1 Check regulations →

Identified Uses

SU24 Scientific research and development

Manufacturers & Suppliers

Alfa Aesar, Thermo Fisher Scientific Chemicals, Inc. logo

Alfa Aesar, Thermo Fisher Scientific Chemicals, Inc.

manufacturer

30 Bond Street, Ward Hill, MA 01835-8099

800-343-0660

http://www.alfa.com

Emergency Contacts

Emergency Contact

(800) 343-0660

Monday-Friday, 8am-7pm EST

Carechem 24

(866) 928-0789

After normal business hours

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 2 H330
Carc. Cat. 1B H350
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2A H319
Flam. Liq. Cat. 4 H227

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H227 Combustible liquid.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H330 Fatal if inhaled.
H350 May cause cancer.

Precautionary Statements

P210 Keep away from flames and hot surfaces. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapors/spray.
P305 + P351 + P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320 Specific treatment is urgent (see on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Chemical characterization: Substances

Chemical Name CAS Number Concentration Hazardous
beta-Propiolactone EC: 200-340-1 57-57-8 100% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate medical advice.

Symptoms: Fatal if inhaled.

Skin contact

Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice.

Symptoms: Causes skin irritation.

Eye contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Symptoms: Causes serious eye irritation.

Ingestion

Seek medical treatment.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

Specific hazards

If this product is involved in a fire, the following can be released: Carbon monoxide and carbon dioxide

Firefighter Protection

Wear self-contained respirator. Wear fully protective impervious suit.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Wear protective equipment. Keep unprotected persons away. Ensure adequate ventilation

Environmental

Do not allow product to reach sewage system or any water course.

Cleanup methods

Absorb with liquid-binding material

Materials: sand, diatomite, acid binders, universal binders, sawdust

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handle under dry protective gas. Keep container tightly sealed. Ensure good ventilation at the workplace. Open and handle container with care.

Storage

Store in freezer (-20°C). Store under dry inert gas. Protect from heat. Store away from water/moisture. Store away from oxidizing agents. This product is moisture sensitive. Keep container tightly sealed. Protect from humidity and water.

Fire prevention

Keep ignition sources away.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.

Hands

Impervious gloves. Check protective gloves prior to each use for their proper condition. The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer.

Eyes

Safety glasses with side shields / NIOSH (US) or EN 166(EU)

Respiratory

Use self-contained respiratory protective device in emergency situations. Recommended filter device for short term use: Use a respirator with multi-purpose combination (US) or type ABEK (EN 14387) as a backup to engineering controls. Risk assessment should be performed to determine if air-purifying respirators are appropriate. Only use equipment tested and approved under appropriate government standards such as NIOSH (USA) or CEN (EU).

Skin/Body

Protective work clothing.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
Liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
---
Colour
---
Colour Intensity
---
Form
Liquid
Odor
Not determined
Odor Threshold
Not determined.
Ph
Not determined.
Melting Point
-34 °℃ (-29 ºF)
Boiling Point
161-163 ℃ (322-325 °F)
Flash Point
70 °℃ (158 °F)
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
Not determined.
Vapor Pressure
3 hPa (2 mm Hg)
Vapor Density
Not determined.
Relative Density
Not determined.
Bulk Density
---
Density
1.146 g/cm3 (9.563 lbs/gal)
Flammability
Not determined.
Upper Explosive Limit
Not determined
Lower Explosive Limit
2.9 Vol %
Explosive Limits
---
Auto Ignition Temperature
Not determined.
Decomposition Temperature
Not determined.
Solubility
Not determined
Partition Coefficient
Not determined.
Solubility In Water
Not determined
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
Not determined.
Kinematic Viscosity
Not determined.
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

The data for this section has not been processed yet.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

Toxicity

Aquatic toxicity: No further relevant information available.

No further relevant information available regarding aquatic toxicity.

Persistence and degradability

No further relevant information available.

No further relevant information available.

Bioaccumulative potential

No further relevant information available.

No further relevant information available.

Mobility in soil

No further relevant information available.

No further relevant information available.

Results of PBT and vPvB assessment

Results of PBT and vPvB assessment PBT: Not applicable. vPvB: Not applicable.

The substance is not considered to be PBT or vPvB.

Other adverse effects

No further relevant information available.

No further relevant information available.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN3382
Shipping Name
Toxic by inhalation liquid, n.o.s. (beta-Propiolactone)
Transport Class
6.1 Toxic substances
Packing Group
I
ADR

Warning: Toxic substances Yes

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The product is classified and labeled in accordance with 29 CFR 1910 (OSHA HCS)

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for beta-Propiolactone?

The signal word is danger.

What is the physical form of beta-Propiolactone?

beta-Propiolactone is a liquid . It has not determined odor.

What is the solubility of beta-Propiolactone?

Not determined

What is beta-Propiolactone used for?

SU24 Scientific research and development

What are the hazard statements for beta-Propiolactone?

This substance has 5 hazard statements:

  • H227: Combustible liquid.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H330: Fatal if inhaled.
  • H350: May cause cancer.

What is the melting point of beta-Propiolactone?

The melting point is -34 °℃ (-29 ºF) and the boiling point is 161-163 ℃ (322-325 °F).