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Safety Data Sheet EN

NucleoSpin RNA (50)

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
NucleoSpin RNA (50)
Product Code
740955.50

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Product for analytical use. Exposure Scenario Classification according REACH, RIP 3.2 Codes: SU 0-2, PC 21, PROC 15, AC 0. The exposure scenario is integrated into sections 1-16.

Uses advised against

not described

Manufacturers & Suppliers

M

MACHEREY-NAGEL

manufacturer

M

MACHEREY-NAGEL GmbH & Co. KG

manufacturer

Valenciennen Str. 11, 52355 Duren, Germany

+49 2421 969 0

Emergency Contacts

Gemeinsames Giftinformationszentrum (GGIZ)

+49 361 730 730

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 3 H226
Acute Tox. Cat. 4 H302
Skin Corr. Cat. 1B H314
Resp. Sens. Cat. 1 H334
Aquatic Chronic Cat. 3 H412
Flam. Liq. Cat. 3 H226
Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
Acute Tox. Cat. 4 H302
Skin Corr. Cat. 1B H314
Aquatic Chronic Cat. 3 H412
Resp. Sens. Cat. 1 H334

GHS Pictograms

GHS02 - Flammable

GHS02

GHS05 - Corrosive

GHS05

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H314 Causes severe skin burns and eye damage.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statements

P260 Do not breathe dust/vapours.
P264 Wash hands thoroughly after handling.
P280 Wear protective gloves/eye protection.
P284 [In case of inadequate ventilation] wear respiratory protection.
P303 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].
P305 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER/doctor.
P405 Store locked up.
P501 Dispose of contents/container to regulated waste treatment.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
guanidine hydrochloride EC: 200-002-3 50-01-1 24 - 36% Yes
ethanol EC: 200-578-6 64-17-5 5 - 35% Yes
guanidinium thiocyanate EC: 209-812-1 593-84-0 5 - 60% Yes
water EC: 231-791-2 7732-18-5 90 - 100% No
rDNase EC: 232-667-0 9003-98-9 90 - 100% Yes
chemicals/mixture until 1% --- 0.1 - 1% No
chemicals/mixture until 2% --- 1 - 2% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation of foam or vapour fresh air should be inhaled. Keep airways free. If vomiting and if insensible place patient in recovery position and keep airways free. Administer a Dexamethasone spray as soon as possible. Ensure quiet, warmth, and provide resuscitation if necessary. In the event of respiratory distress ensure that the patient inhales oxygen. Secure the breathing, heart and circulatory function.

Symptoms: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Skin contact

Remove contaminated clothing immediately. Rinse the affected skin or mucous membrane thoroughly for min. 15 minutes under running water. (If possible) use soap. Avoid neutralisation. Then apply a loose bandage.

Symptoms: Rapid penetration and destruction of the skin. Especially in the heated form. Causes severe skin burns.

Eye contact

After contact with the eyes rinse thoroughly under running water with the eyelid wide open for min. 10 minutes with eye washing bottle, eye douche or running water (protect intact eye). Before (if possible) apply eye drops Proxymetacaine 0.5%, if the opening the eyelid convulsion is painful. Further treatment to be carried out by an eye specialist.

Symptoms: Causes severe eye damage.

Ingestion

After oral intake lots of water with activated charcoal supplement should be drunk after it has been ingested. Do not induce vomiting under any circumstances. Do not make any efforts to neutralise it. Contact medical advice for possible consequences.

Immediate Medical Attention

Contact medical advice for possible consequences. Further treatment to be carried out by an eye specialist.

Medical Treatment

Administer a Dexamethasone spray as soon as possible. In the event of respiratory distress ensure that the patient inhales oxygen. Secure the breathing, heart and circulatory function. Before (if possible) apply eye drops Proxymetacaine 0.5%, if the opening the eyelid convulsion is painful.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

FOAM, WATER SPRAY, DRY POWDER, CARBON DIOXIDE

Specific hazards

Flammable (GHS regulation). May form explosive vapour-air mixtures. Formation of hazardous and caustic vapour-air mixtures possible.

Instructions

Spray any vapours released with water. Retent fire water.

Firefighter Protection

Use only acid-resistant safety equipment. For great amount - if necessary - protective breathing apparatus which is independent of the ambient air (isolated equipment), and sealed protective clothing is necessary in the event of a large-scale formation of toxic substances.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Regular staff training is necessary, indicating hazards and precautions on the basis of operating instructions. Restrictions on activity must be observed.

Small spill

Collect small amounts of leaked liquid and flush with water into drains.

Environmental

Should not be released into the environment.

Cleanup methods

Clean any contaminated equipment and floors with plenty of water. Collect small amounts of leaked liquid and flush with water into drains.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handling in accordance with the test instruction, that comes with the product.

Storage

Safe storage is guaranteed in the original packaging from MACHEREY-NAGEL. Keep original product packages tightly closed during handling and storage.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Good ventilation and extraction system in the room, floor resistant to chemicals with floor drainage and washing facilities.

Hands

Yes, gloves according EN 374 (permeation time >30 min - level 2), consist of PVC, natural latex, Neopren, or Nitril (f.ex. from Ansell or KCL). Use for short times chemical resistant latex gloves with code EN 374-3 level 1.

Eyes

Yes, safety glasses according EN 166 with integrated side shields or wrap-around protection or face protection.

Respiratory

Use for open access of these substances for example a protection filter, class A/AX. No additional recommendations.

Skin/Body

Recommended to avoid clothing damage, and to avoid contamination with these hazards.

Environmental

Do not release product into environment.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Properties Status
---
Physical State Data
liquid
Vapor Density
---
Boiling Point
no data available
Molecular Weight
---
Appearance
---
Freezing Point
---
Voc Content
---
Odor Threshold
---
Decomposition Temperature
---
Vapor Pressure
---
Cloud Point
---
Kinematic Viscosity
no data available
Bulk Density
---
Relative Density
---
Melting Point
no data available
Physical State
liquid
Solidification Point
---
Solubility In Fat
---
Softening Point
---
Explosive Limits
---
Auto Ignition Temperature
---
Upper Explosive Limit
no data available
Flammability
no data available
Ph
6.5-7.5
Solubility In Water
no data available
Crystallisation Point
---
Flash Point
28 °C
Odor
alcoholic
Lower Explosive Limit
no data available
Colour
colourless
Metal Corrosion
Substances are highly corrosive.
Colour Intensity
---
Solubility
---
Relative Evaporation Rate
---
Evaporation Rate
---
Density
1.03-1.06 g/cm³
Dynamic Viscosity
---
Partition Coefficient
---
State Under Standard Conditions
---
Form
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

no known instability.

Reactivity

no further data available.

Hazardous reactions

Can react violently with organic material. Note: Can form very reactive substances with oxidizing agents. Possible: &H:EUH031& No further data available.

Avoid

No more required.

Incompatible

no additional data available

Decomposition

Decompositions are not observed during the expiration period under recommended conditions.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
1993
Shipping Name
Flammable liquid, n.o.s. (ethanol mixture)
Transport Class
3
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for NucleoSpin RNA (50)?

The signal word is danger.

What is the physical form of NucleoSpin RNA (50)?

NucleoSpin RNA (50) is a liquid with colourless color. It has alcoholic odor.

What is NucleoSpin RNA (50) used for?

Product for analytical use. Exposure Scenario Classification according REACH, RIP 3.2 Codes: SU 0-2, PC 21, PROC 15, AC 0. The exposure scenario is integrated into sections 1-16.

What are the hazard statements for NucleoSpin RNA (50)?

This substance has 2 hazard statements:

  • H314: Causes severe skin burns and eye damage.
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

What is the melting point of NucleoSpin RNA (50)?

The melting point is no data available and the boiling point is no data available.