Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- NucleoSpin DNA RapidLyse (50)
- Product Code
- 740100.50
Regulatory Identifiers
- CAS Number
- N/A
- REACH No.
- A registration number for the substance(s) does not exist because the annual tonnage does not require registration or the substance or its use is excluded from registration.
- UFI Code
- TTWV-43C9-R202-NTGN, D0HW-E3PF-P200-V61A, GXGW-X302-C20G-6UF8
Identified Uses
Product for analytical use. Exposure Scenario Classification according REACH, RIP 3.2 Codes: SU 0-2, PC 21, PROC 15, AC 0 The exposure scenario is integrated into sections 1-16.
Uses advised against
not described
Manufacturers & Suppliers
MACHEREY-NAGEL GmbH & Co. KG
manufacturer
Valenciennen Str. 11, 52355 Düren, Germany
+49 2421 969 0
Emergency Contacts
Gemeinsames Giftinformationszentrum (GGIZ)
+49 361 730 730
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS02
GHS05
GHS07
GHS08
GHS09
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
NucleoSpin DNA RapidLyse (50) is a kit containing multiple components (RLB, RLY, RLW, RLE, Proteinase K).
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| 1-dodecylpyridiniumchloride EC: 203-232-2 | 104-74-5 | 2.5 - 5% | Yes |
| guanidinium thiocyanate EC: 209-812-1 | 593-84-0 | 30 - 45% | Yes |
| ethanol EC: 200-578-6 | 64-17-5 | 5 - 20% | Yes |
| dodecyl sulfate, sodium salt EC: 205-788-1 | 151-21-3 | 2.5 - 3% | Yes |
| dodecyl sulfate, sodium salt EC: 205-788-1 | 151-21-3 | 1 - 2.5% | No |
| proteinase K, liquid EC: 254-457-8 | 39450-01-6 | 1 - 3% | Yes |
| glycerole EC: 200-289-5 | 56-81-5 | 10 - 50% | No |
| chemicals/mixture until 1% | --- | 0.1 - 1% | No |
Notes
When not listed, mixtures are added with water [CAS No. 7732-18-5] to 100%.
First Aid Measures
Emergency procedures for chemical exposure incidents
After inhalation of foam or vapour fresh air should be inhaled. Keep airways free. If vomiting and if insensible place patient in recovery position and keep airways free. Administer a Dexamethasone spray as soon as possible. Ensure quiet, warmth, and provide resuscitation if necessary. In the event of respiratory distress ensure that the patient inhales oxygen. Secure the breathing, heart and circulatory function.
Symptoms: respiratory distress
Remove contaminated clothing immediately. Rinse the affected skin or mucous membrane thoroughly for min. 15 minutes under running water. (If possible) use soap. Avoid neutralisation. Then apply a loose bandage.
Symptoms: Rapid penetration and destruction of the skin. Especially in the heated form. Causes severe skin burns.
After contact with the eyes rinse thoroughly under running water with the eyelid wide open for min. 10 minutes with eye washing bottle, eye douche or running water (protect intact eye). Before (if possible) apply eye drops Proxymetacaine 0.5%, if the opening the eyelid convulsion is painful. Further treatment to be carried out by an eye specialist.
Symptoms: convulsion
After oral intake lots of water with activated charcoal supplement should be drunk after it has been ingested. Do not induce vomiting under any circumstances. Do not make any efforts to neutralise it. Contact medical advice for possible consequences.
Immediate Medical Attention
Contact medical advice for possible consequences. Take to a doctor, in a raised position if there are breathing difficulties.
Medical Treatment
Further treatment to be carried out by an eye specialist. Administer a Dexamethasone spray as soon as possible. In the event of respiratory distress ensure that the patient inhales oxygen. Secure the breathing, heart and circulatory function.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Fire extinguishers appropriate to the fire classification, and, if applicable, a fire blanket must be available in a prominent location in the work area. All extinguishers like FOAM, WATER SPRAY, DRY POWDER, CARBON DIOXIDE can be used.
no data available
Flammable (GHS regulation). May form explosive vapour-air mixtures. Formation of hazardous and caustic vapour-air mixtures possible.
Spray any vapours released with water. Retent fire water. Use only acid-resistant safety equipment.
Firefighter Protection
For great amount - if necessary - protective breathing apparatus which is independent of the ambient air (isolated equipment), and sealed protective clothing is necessary in the event of a large-scale formation of toxic substances.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Regular staff training is necessary, indicating hazards and precautions on the basis of operating instructions. Restrictions on activity must be observed.
Collect small amounts of leaked liquid and flush with water into drains.
Should not be released into the environment.
Clean any contaminated equipment and floors with plenty of water.
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---
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Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Handling in accordance with the test instruction, that comes with the product.
Safe storage is guaranteed in the original packaging from MACHEREY-NAGEL. Keep original product packages tightly closed during handling and storage.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Good ventilation and extraction system in the room, floor resistant to chemicals with floor drainage and washing facilities.
Yes, gloves according EN 374 (permeation time >30 min - level 2), consist of PVC, natural latex, Neopren, or Nitril (f.ex. from Ansell or KCL). Use for short times chemical resistant latex gloves with code EN 374-3 level 1.
Yes, safety glasses according EN 166 with integrated side shields or wrap-around protection or face protection.
Use for open access of these substances for example a protection filter, class A/AX. No additional recommendations.
Recommended to avoid clothing damage, and to avoid contamination with these hazards.
Do not release product into environment.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
no known instability.
no further data available.
Can react violently with organic material. Note: Can form very reactive substances with oxidizing agents. Possible: &H:EUH031&
No more required.
no additional data available
In the original package all parts/all reagents are safety and separated stored. Decompositions are not observed during the expiration period under recommended conditions.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
The data for this section has not been processed yet.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
Regulatory Information
Chemical regulations, safety assessments, and compliance status
The data for this section has not been processed yet.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for NucleoSpin DNA RapidLyse (50)?
The signal word is danger.
What is the physical form of NucleoSpin DNA RapidLyse (50)?
NucleoSpin DNA RapidLyse (50) is a liquid with colourless (rly, rlw, rle, proteinase k), slightly yellow (rlb) color. It has odorless (rly, rlw, rle, proteinase k), alcoholic (rlb) odor.
What is NucleoSpin DNA RapidLyse (50) used for?
Product for analytical use. Exposure Scenario Classification according REACH, RIP 3.2 Codes: SU 0-2, PC 21, PROC 15, AC 0 The exposure scenario is integrated into sections 1-16.
What are the hazard statements for NucleoSpin DNA RapidLyse (50)?
This substance has 3 hazard statements:
- H314: Causes severe skin burns and eye damage.
- H317: May cause an allergic skin reaction.
- H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
What is the melting point of NucleoSpin DNA RapidLyse (50)?
The melting point is no data available and the boiling point is no data available.