NextSDS Logo
Safety Data Sheet EN

Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP

CAS 6381-92-6

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report.

Get Free Audit
01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP
Product Code
108421
Chemical Name
ethylenedinitrilotetraacetic acid disodium salt dihydrate

Regulatory Identifiers

CAS Number
6381-92-6 Check regulations →
REACH No.
01-2119486775-20-XXXX

Identified Uses

Pharmaceutical production, Cosmetic raw material

Manufacturers & Suppliers

M

Merck Chemicals Ltd

regional supplier

Boulevard Industrial Park, Padge Road, Beeston, Nottingham, NG9 2JR

01159 430840

E

EQ-RS

Emergency Contacts

Emergency Contact

+49 (0) 6151 722440

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H332
STOT RE Cat. 2 H373

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H332 Harmful if inhaled.
H373 May cause damage to organs (Respiratory Tract) through prolonged or repeated exposure if inhaled.

Precautionary Statements

P314 Get medical advice/ attention if you feel unwell.

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report

Free Audit
03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Disodium dihydrogen ethylenediaminetetraacetate dihydrate EC: 205-358-3 6381-92-6 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/shower.

Eye contact

rinse out with plenty of water.

Ingestion

immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention

Call in physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapours/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture. Observe label precautions.

Storage

Tightly closed. Dry.

Hygiene

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Technical measures and appropriate working operations should be given priority over the use of personal protective equipment. See section 7.1.

Hands

full contact: Glove material: Nitrile rubber, Glove thickness: 0.11 mm, Break through time: > 480 min; splash contact: Glove material: Nitrile rubber, Glove thickness: 0.11 mm, Break through time: > 480 min. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril® L (full contact), KCL 741 Dermatril® L (splash contact). The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types. This recommendation applies only to the product stated in the safety data sheet supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Safety glasses

Respiratory

required when dusts are generated. Recommended Filter type: Filter P 2 (acc. to DIN 3181) for solid and liquid particles of harmful substances. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
---
Colour
white
Colour Intensity
---
Form
crystals
Odor
odourless
Odor Threshold
Not applicable
Ph
4 - 5 at 50 g/l 20 °C
Melting Point
110 °C Elimination of water of crystallisation
Boiling Point
Not applicable, (decomposition)
Flash Point
No information available.
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No information available.
Vapor Pressure
No information available.
Vapor Density
---
Relative Density
No information available.
Bulk Density
ca.700 kg/m³
Density
No information available.
Flammability
No information available.
Upper Explosive Limit
No information available.
Lower Explosive Limit
No information available.
Explosive Limits
---
Auto Ignition Temperature
No information available.
Decomposition Temperature
255 °C
Solubility
---
Partition Coefficient
No information available.
Solubility In Water
100 g/l at 20 °C
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
No information available.
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature) .

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: Strong oxidizing agents

Avoid

Strong heating.

Incompatible

Aluminium, Copper, Copper alloys, Nickel, Zinc

Decomposition

releases water of crystallisation when heated.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP?

The signal word is warning.

What is the physical form of Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP?

Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP is a solid with white color. It has odourless odor.

What is Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP used for?

Pharmaceutical production, Cosmetic raw material

What are the hazard statements for Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP?

This substance has 2 hazard statements:

  • H332: Harmful if inhaled.
  • H373: May cause damage to organs (Respiratory Tract) through prolonged or repeated exposure if inhaled.

What is the melting point of Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate) suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP?

The melting point is 110 °C Elimination of water of crystallisation and the boiling point is Not applicable, (decomposition).