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Safety Data Sheet EN

TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT

CAS 1185-53-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT
Product Code
T3253

Regulatory Identifiers

CAS Number
1185-53-1 Check regulations →

Identified Uses

Laboratory chemicals, Synthesis of substances

Manufacturers & Suppliers

S

Sigma-Aldrich Inc.

manufacturer

3050 SPRUCE ST, ST. LOUIS MO 63103, UNITED STATES

+1 314 771-5765

Emergency Contacts

CHEMTREC

800-424-9300

24 Hours/day; 7 Days/week

CHEMTREC

+1-703-527-3887

24 Hours/day; 7 Days/week

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified no signal word

GHS Pictograms

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

No components need to be disclosed according to the applicable regulations.

Chemical Name CAS Number Concentration Hazardous
Substance EC: 214-684-5 1185-53-1 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Eye contact

rinse out with plenty of water. Remove contact lenses.

Ingestion

make victim drink water (two glasses at most). Consult doctor if feeling unwell.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas. Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

In the event of fire, wear self-contained breathing apparatus.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

For precautions see section 2.2.

Storage

Tightly closed. Dry.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L.

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

Recommended Filter type: Filter type P1; required when dusts are generated. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
solid
Physical State Data
solid
State Under Standard Conditions
---
Appearance
crystalline
Colour
white
Colour Intensity
---
Form
crystalline
Odor
odorless
Odor Threshold
Not applicable
Ph
No data available
Melting Point
ca.150.7 °C (ca.303.3 °F) at ca.1,013 hPa - OECD Test Guideline 102
Boiling Point
225 - 295 °C 437 - 563 °F at ca.1,013 hPa - OECD Test Guideline 103 - Decomposition
Flash Point
()Not applicable
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
< 0.1 hPa at 50 °C (122 °F) - OECD Test Guideline 104
Vapor Density
No data available
Relative Density
No data available
Bulk Density
---
Density
ca.1.28 g/cm³ at 20.2 °C (68.4 °F) - OECD Test Guideline 109
Flammability
---
Upper Explosive Limit
---
Lower Explosive Limit
---
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
ca.230 °C (ca.446 °F) -
Solubility
---
Partition Coefficient
log Pow: ca.-3.6 at 20 °C (68 °F) - OECD Test Guideline 107 - n-octanol/water Bioaccumulation is not expected.
Solubility In Water
ca.561 g/l at 20 °C (68 °F) - OECD Test Guideline 105 - soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

hygroscopic. The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Risk of dust explosion. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

Violent reactions possible with: Strong oxidizing agents

Avoid

no information available

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - 460 mg/l - 96 h (OECD Test Guideline 203) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: Tris(hydroxymethyl)aminomethane Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - > 117 mg/l - 48 h (OECD Test Guideline 202) Toxicity to bacteria static test EC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d Result: 97.1 % - Readily biodegradable. (OECD Test Guideline 301F)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available
13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Waste material must be disposed of in accordance with the national and local regulations.

Disposal

Leave chemicals in original containers. No mixing with other waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT?

The signal word is no signal word.

What is the physical form of TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT?

TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT is a solid appearing as crystalline with white color. It has odorless odor.

What is TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT used for?

Laboratory chemicals, Synthesis of substances

What is the melting point of TRIS (HYDROXYMETHYL) AMINOMETHANE HYDROCHLORIDE SALT?

The melting point is ca.150.7 °C (ca.303.3 °F) at ca.1,013 hPa - OECD Test Guideline 102 and the boiling point is 225 - 295 °C 437 - 563 °F at ca.1,013 hPa - OECD Test Guideline 103 - Decomposition.