Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- NEONATAL Biotinidase Screening Assay
- Product Code
- E-KH-480-1920
Regulatory Identifiers
- CAS Number
- N/A
Identified Uses
For in vitro diagnostic use only
Manufacturers & Suppliers
LaCAR MDx technologies
manufacturer
Liège Science Park, Rue des Chasseurs Ardennais,10, 4031 Liège, Belgium
+32 (0) 4 287 39 44
Emergency Contacts
Emergency Contact
+1 703 527 3887
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS05
GHS07
GHS08
GHS09
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| EDTA EC: 205-358-3 | 6381-92-6 | 1% | Yes |
| Sodium nitrite EC: 231-555-9 | 7632-00-0 | --- | Yes |
| Boric acid EC: 233-139-2 | 10043-35-3 | 100% | Yes |
| Sulfuric acid EC: 231-639-5 | 7664-93-9 | 15% | Yes |
| NED EC: 215-981-2 | 1465-25-4 | 1% | Yes |
| Tricholoracetic acid (TCA) EC: 200-927-2 | 76-03-9 | 1% | Yes |
First Aid Measures
Emergency procedures for chemical exposure incidents
Move to fresh air. Call a physician. If breathing is difficult, supply oxygen.
Take off immediately all contaminated clothing. Rinse skin with water/shower. For specific reagents: wash abundantly with soap and water, rinse thoroughly, and disinfect with a 1/10 dilution of 12% liquid bleach. Leave the disinfectant in contact for 5 minutes. Consult a hospital emergency medical department immediately.
Rinse immediately with plenty of water, keeping the eyelids wide open for at least 15 minutes. Remove contact lenses. Call in ophthalmologist or doctor immediately.
Make victim drink water (two glasses at most). Do not induce vomiting (risk of perforation). Do not attempt to neutralise. Consult a physician or hospital emergency medical department immediately.
Immediate Medical Attention
Consult a physician or hospital emergency medical department immediately.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Boric acid: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Sulfuric acid: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Trichloroacetic acid: Water, Foam, Carbon dioxide (CO2), Dry powder.
For this substance/mixture no limitations of extinguishing agents are given.
Borane/boron oxides, Sulfur oxides, Carbon oxides, Hydrogen chloride gas. Fire may cause evolution of boron compounds, sulfur oxides, and hazardous combustion gases or vapours.
Suppress (knock down) gases / vapors / mists with a water spray jet.
Firefighter Protection
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
Do not let product enter drains.
Take up carefully. Dispose of properly. Clean up affected area. Take up with liquid-absorbent and neutralising material (e.g. Chemizorb® H⁺, Merck Art. No. 101595).
Materials: liquid-absorbent and neutralising material (e.g. Chemizorb® H⁺, Merck Art. No. 101595)
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Work under hood. Do not inhale substance/mixture.
Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. No metal containers.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Boric acid: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L. Sulfuric acid: Full contact: Viton®, Minimum layer thickness: 0,7 mm, Break through time: 480 min, Material tested: Vitoject® (KCL 890 / Aldrich Z677698, Size M); Splash contact: butyl-rubber, Minimum layer thickness: 0,7 mm, Break through time: 120 min, Material tested: Butoject® (KCL 898). Trichloroacetic acid: Nitrile rubber, Minimum layer thickness: 0,11 mm, Break through time: 480 min, Material tested: KCL 741 Dermatril® L.
Boric acid: Safety glasses (tested and approved under NIOSH (US) or EN 166(EU)). Sulfuric acid: Tightly fitting safety goggles (tested and approved under NIOSH (US) or EN 166(EU)). Trichloroacetic acid: Tightly fitting safety goggles (tested and approved under NIOSH (US) or EN 166(EU)).
Boric acid: Required when dusts are generated, Filter type P3. Sulfuric acid: Required when vapours/aerosols are generated, Filter B-(P2). Trichloroacetic acid: Filter type B. Standards: DIN EN 143, DIN 14387 and other accompanying standards.
Boric acid: Protective clothing. Sulfuric acid: Acid-resistant protective clothing. Trichloroacetic acid: Acid-resistant protective clothing.
Do not let product enter drains.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
The products are chemically stable under standard ambient conditions (room temperature).
Boric acid (CAS-No: 10043-35-3): No data available; Sulfuric acid (CAS-No: 7664-93-9): Has a corrosive effect Strong oxidising agent; Tricholoracetic acid (CAS No: 76-03-9): The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Boric acid: Risk of explosion with: Acetic anhydride; Violent reactions possible with: Strong oxidising agents, Bases. Sulfuric acid: A risk of explosion and/or of toxic gas formation exists with the following substances: Alkali metals, Alkali compounds, Ammonia, Aldehydes, Acetonitrile, Alkaline earth metals, Alkalines, Acids, Alkaline earth compounds, Metals, Metal alloys, Oxides of phosphorus, Phosphorus, Hydrides, Halogen-halogen compounds, Oxyhalogenic compounds, Permanganates, nitrates, Carbides, Combustible substances, Organic solvent, Acetylidene, Nitriles, Organic nitro compounds, Anilines, Peroxides, Picrates, Nitrides, Lithium silicide, Iron(III) compounds, Bromates, Chlorates, Amines, Perchlorates, Hydrogen peroxide. Trichloroacetic acid: Risk of explosion with: Silver salt; Exothermic reaction with: alkalines, alkali hydroxides, Amines, Strong oxidizing agents, sulfoxides, dimethyl sulfoxide with Copper.
Boric acid: no information available; Sulfuric acid: no information available; Tricholoracetic acid: Exposure to moisture, Heat.
Boric acid: Potassium, Acid anhydrides; Sulfuric acid: Animal/vegetable tissues, Metals (Contact with metals liberates hydrogen gas); Trichloroacetic acid: Metals
In the event of fire: see section 5.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
12.1. Toxicity
12.1. Toxicity
12.2. Persistence and degradability
12.3. Bioaccumulative potential
12.4. Mobility in soil
12.5. Results of PBT and vPvB assessment
The substances/mixtures do not contain PBT or vPvB components at concentrations of 0.1% or higher.
12.6. Endocrine disrupting properties
The substances listed do not contain components considered to have endocrine disrupting properties at levels of 0.1% or higher, with the exception of Tricholoracetic acid for which no data is available.
12.7. Other adverse effects
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
No data available for Boric acid (CAS-No: 10043-35-3)
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- 1830
- Shipping Name
- SULPHURIC ACID
- Transport Class
- 8
- Packing Group
- II
Regulatory Information
Chemical regulations, safety assessments, and compliance status
This safety datasheet complies with the requirement of Regulation (EC) No 1907/2006.
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for NEONATAL Biotinidase Screening Assay?
The signal word is danger.
What is the physical form of NEONATAL Biotinidase Screening Assay?
NEONATAL Biotinidase Screening Assay is a solid, liquid, solid appearing as white (boric acid), colorless (sulfuric acid), off-white (trichloroacetic acid) with white, colorless, off-white color. It has odorless, odorless, stinging odor.
What is NEONATAL Biotinidase Screening Assay used for?
For in vitro diagnostic use only
What are the hazard statements for NEONATAL Biotinidase Screening Assay?
This substance has 7 hazard statements:
- H290: May be corrosive to metals.
- H314: Causes severe skin burns and eye damage.
- H318: Causes serious eye damage.
- H335: May irritate the respiratory tract.
- H360FD: May damage fertility. May damage the unborn child.
- H400: Very toxic to aquatic life.
- H410: Very toxic to aquatic organisms, causes effects.
What is the melting point of NEONATAL Biotinidase Screening Assay?
The melting point is Boric acid: > 1.000 °C - Regulation (EC) No. 440/2008, Annex, A.1; Sulfuric acid: -20 °C; Trichloroacetic acid: 54-58°C – lit and the boiling point is Trichloroacetic acid: 196°C - lit.