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Safety Data Sheet EN

BD FACS™ Lysing Solution

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
BD FACS™ Lysing Solution
Product Code
349202

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Scientific and industrial laboratory use. For In Vitro Diagnostic Use.

Uses advised against

None known.

Manufacturers & Suppliers

B

Becton Dickinson France S.A.S. Belgian Branch

manufacturer

Erembodegem-Dorp 86, 9320 Erembodegem, Belgium

32 2 400 98 95

Emergency Contacts

Emergency Contact

32 2 400 98 95

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302
Acute Tox. Cat. 4 H312
Acute Tox. Cat. 4 H332
Skin Corr. Cat. 1B H314
Eye Dam. Cat. 1 H318
Skin Sens. Cat. 1 H317
Muta. Cat. 2 H341
Carc. Cat. 1B H350
STOT SE Cat. 1 H370
STOT SE Cat. 3 H335
STOT RE Cat. 2 H373

GHS Pictograms

GHS05 - Corrosive

GHS05

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H335 May cause respiratory irritation.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
H370 Causes damage to organs.
H373 May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapors/spray.
P264 Wash face, hands and any exposed skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P307 + P311 IF exposed: Call a POISON CENTER or doctor/ physician.
P308 + P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER/doctor.
P312 Call a POISON CENTER or doctor/ physician if you feel unwell.
P333 + P313 If skin irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/ container to an approved facility in accordance with local, regional, national and international regulations.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Ethanol, 2,2'-oxybis- 111-46-6 25 - 50% Yes
Formaldehyde 50-00-0 5 - 10% Yes
Methanol 67-56-1 3 - 5% Yes

Notes

All concentrations are percent by weight unless ingredient is a gas. Gas concentrations are in percent by volume.

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move the exposed person to fresh air at once. Get medical attention immediately.

Skin contact

Wash off promptly and flush contaminated skin with water. Promptly remove clothing if soaked through and flush skin with water. Get medical attention immediately.

Eye contact

Important! Immediately rinse with water for at least 15 minutes. Get medical attention immediately. Continue to rinse.

Ingestion

If swallowed, rinse mouth with water (only if the person is conscious). Call a physician or poison control center immediately.

Immediate Medical Attention

Get immediate medical advice/attention. Get medical attention immediately. Get medical attention immediately. Get medical attention immediately. Call a physician or poison control center immediately.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray, fog, CO2, dry chemical, or alcohol resistant foam.

Unsuitable media

Avoid water in straight hose stream; will scatter and spread fire.

Specific hazards

Fire or excessive heat may produce hazardous decomposition products.

Instructions

No unusual fire or explosion hazards noted.

Firefighter Protection

Firefighters must use standard protective equipment including flame retardant coat, helmet with face shield, gloves, rubber boots, and in enclosed spaces, SCBA.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Ensure suitable personal protection (including respiratory protection) during removal of spillages in a confined area.

Environmental

Contact local authorities in case of spillage to drain/aquatic environment.

Cleanup methods

Sweep up and place in a clearly labeled container for chemical waste.

—

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe dust/fume/gas/mist/vapors/spray. Do not get in eyes, on skin, on clothing. Do not eat, drink or smoke when using the product. Read and follow manufacturer's recommendations. Wash promptly with soap and water if skin becomes contaminated. Use personal protective equipment as required.

Storage

Store in tightly closed original container in a dry, cool and well-ventilated place. Should be stored separately from oxidizers, bases, and food chemical substances Keep in a cool, ventilated location far from heat source and flame

Hygiene

Do not eat, drink or smoke when using the product. Wash promptly with soap and water if skin becomes contaminated.

Fire prevention

Keep in a cool, ventilated location far from heat source and flame

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Adequate ventilation should be provided so that exposure limits are not exceeded.

Hands

Material: Use suitable protective gloves if risk of skin contact.

Eyes

Wear safety glasses with side shields (or goggles). A - Safety Glasses

Respiratory

If engineering controls do not maintain airborne concentrations below recommended exposure limits (where applicable) or to an acceptable level (in countries where exposure limits have not been established), an approved respirator must be worn.

Skin/Body

Wear appropriate clothing to prevent reasonably probable skin contact. Wear chemical-resistant gloves and protective clothing appropriate for the risk of exposure. Recommended gloves:

Environmental

Data available upon request.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Language Code
---
Physical State
liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
Colorless to yellow
Colour
Colorless to yellow
Colour Intensity
---
Form
liquid
Odor
Slight odor
Odor Threshold
No data available.
Ph
7.10 - 7.80
Melting Point
---
Boiling Point
---
Flash Point
295 °F/146 °C
Freezing Point
No data available.
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
23 hPa (68 °F/20 °C)
Vapor Density
---
Relative Density
---
Bulk Density
No data available.
Density
1 g/cm3
Flammability
No data available.
Upper Explosive Limit
No data available.
Lower Explosive Limit
No data available.
Explosive Limits
---
Auto Ignition Temperature
No data available.
Decomposition Temperature
No data available.
Solubility
Soluble
Partition Coefficient
No data available.
Solubility In Water
Soluble
Solubility In Fat
---
Molecular Weight
---
Voc Content
EU. Directive 2010/75/EU on Industrial Emissions (IPPC), Annex II, L 334/17: 0 % (calculated) EC Directive 2004/42: 445.52 g/l ~44.55 % (calculated)
Metal Corrosion
---
Dynamic Viscosity
No data available.
Kinematic Viscosity
No data available.
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

No data available.

Reactivity

No data available.

Hazardous reactions

Do not subject to grinding/shock/friction/. Contact with acids and metals can lead to violent decomposition.

Avoid

grinding/shock/friction/

Incompatible

acids and metals

Decomposition

By fire, toxic gases may be formed (COx, NOx).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

12.1 Toxicity

Ethanol, 2,2'-oxybis- - LC 50 (Pimephales promelas, 96 h): 75,200 mg/l - LC 50 (Pimephales promelas, 96 h): 75,200 mg/l Experimental result, Key study - LC 50 (Western mosquitofish (Gambusia affinis), 48 h): > 32,000 mg/l Mortality - LC 50 (Carp (Leuciscus idus melanotus), 48 h): > 10,000 mg/l Mortality - LC 50 (Western mosquitofish (Gambusia affinis), 24 h): > 32,000 mg/l Mortality

12.1 Toxicity

Formaldehyde - LC 50 (Morone saxatilis, 96 h): 6.7 mg/l Experimental result, Key study

12.1 Toxicity

Methanol - LC 50 (Pimephales promelas, 96 h): 29,400 mg/l - EC 50 (Pimephales promelas, 96 h): 28,900 mg/l Experimental result, Supporting study - LC 50 (Pimephales promelas, 48 h): 28,400 mg/l Experimental result, Supporting study - LC 50 (Pimephales promelas, 96 h): 28,100 mg/l Experimental result, Supporting study LC 50 (Trachinotus carolinus, 24 h): 10,112 mg/l Experimental result, Supporting study

12.1 Toxicity

Product: The product contains a substance which is toxic to aquatic organisms. Components: - Ethanol, 2,2'-oxybis- Formaldehyde

12.1 Toxicity

- Methanol - LC 50 (Brine shrimp (Artemia salina), 24 h): > 10,000 mg/l Mortality

12.1 Toxicity

- EC 50 (Daphnia pulex, 48 h): 5.8 mg/l Experimental result, Key study experimental result

12.1 Toxicity

- EC 50 (Green algae (Scenedesmus subspicatus), 72 h): 4.89 mg/l - No data available. ## Toxicity to microorganisms

12.1 Toxicity

- LC 50 (Turbellarian, flatworm (Dugesia tigrina), 96 h): > 100 mg/l - Mortality

12.1 Toxicity

- Not expected to be harmful to aquatic organisms.

Not expected to be harmful to aquatic organisms.

12.1 Toxicity

LC 50 (Danio rerio, 144 h): 6.9 mg/l (semi-static) Experimental result, Supporting study experimental result - No data available.

12.1 Toxicity

## Aquatic Invertebrates ### Product: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. ### Components: - Ethanol, 2,2'-oxybis- Formaldehyde - Methanol

Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

12.1 Toxicity

- LOAEL (Ceriodaphnia dubia, 7 d): 6 mg/l Experimental result, Not specified experimental result - No data available.

12.2 Persistence and degradability

12.3 Bioaccumulative potential

12.4 Mobility in soil

12.5 Results of PBT and vPvB assessment

12.6 Endocrine disrupting properties

12.7 Other adverse effects

12.1 Toxicity

Methanol No data available. No data available. LC 50 (Turbellarian, flatworm (Dugesia tigrina), 96 h): > 100 mg/l

12.2 Persistence and Degradability

Biodegradation Product: No data available.

No data available.

12.2 Persistence and Degradability

Components: Ethanol, 2,2'-oxybis- 90 - 100 % (28 d) Experimental result, Weight of Evidence study Detected in water. 25 - 92 % (28 d) Read-across based on grouping of substances (category approach), Weight of Evidence study Detected in water. 70 - 80 % (28 d) Experimental result, Weight of Evidence study Detected in water. 90 - 100 % (20 d) Read-across based on grouping of substances (category approach), Weight of Evidence study Detected in water. 90 - 100 % (10 d) Read-across based on grouping of substances (category approach), Weight of Evidence study Detected in water.

12.2 Persistence and Degradability

Formaldehyde Readily biodegradable 97 % (2 Weeks) Experimental result, Key study Detected in water.

12.2 Persistence and Degradability

Methanol 84 % Experimental result, Key study Detected in water. 46.3 % (5 d) Experimental result, Supporting study Soil 69 % Experimental result, Key study Detected in water. 71.5 % (5 d) Experimental result, Key study Detected in water. 82.7 % (5 d) Experimental result, Key study Detected in water. ### BOD/COD Ratio

12.3 Bioaccumulative potential

### Bioconcentration Factor (BCF) Product: No data available. Components: Ethanol, 2,2'-oxybis-

No data available for the product. Components listed: Ethanol, 2,2'-oxybis-.

12.3 Bioaccumulative potential

Formaldehyde Will not bio-accumulate.

Formaldehyde will not bio-accumulate.

12.3 Bioaccumulative potential

Methanol Green algae (Chlorella fusca vacuolata), Bioconcentration Factor (BCF): 28,400 (Static) Partition Coefficient n-octanol / water (log Kow)

12.3 Bioaccumulative potential

Methanol Log Kow: 0.35 Log Kow: -0.77

12.4 Mobility in soil

Product: No data available. Components: Ethanol, 2,2'-oxybis- Formaldehyde No data available. Methanol No data available.

No data available.

12.5 Results of PBT and vPvB assessment

Product: No data available. Components:

No data available.

12.5 Results of PBT and vPvB assessment

Ethanol, 2,2'-oxybis- Formaldehyde No data available. Methanol Not fulfilling PBT (persistent/bioaccumulative/toxic) criteria, Not fulfilling vPvB (very persistent/very bioaccumulative) criteria Methanol No data available.

Methanol does not fulfill PBT (persistent/bioaccumulative/toxic) criteria or vPvB (very persistent/very bioaccumulative) criteria.

12.6 Other adverse effects

Other hazards Product: No data available.

No data available.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose of waste at a facility with special permission to dispose industrial wastes subject to special control. Waste should be accompanied by a manifest for the industrial wastes.

Disposal

This material and its container must be disposed of as hazardous waste.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

EU. REACH Annex XIV, Substances Subject to Authorization: None present or none present in regulated quantities. EU. REACH Candidate List of Substances of Very High Concern for Authorization (SVHC): None present or none present in regulated quantities. EU. Regulation 2019/1021/EU on persistent organic pollutants (POPs) (recast), as amended: None present or none present in regulated quantities. Regulation 1005/2009/EC on substances that deplete the ozone layer, Annex I, Controlled Substances: None present or none present in regulated quantities. Regulation 1005/2009/EC on substances that deplete the ozone layer, Annex II, New Substances: None present or none present in regulated quantities.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for BD FACS™ Lysing Solution?

The signal word is danger.

What is the physical form of BD FACS™ Lysing Solution?

BD FACS™ Lysing Solution is a liquid appearing as colorless to yellow with colorless to yellow color. It has slight odor odor.

What is the solubility of BD FACS™ Lysing Solution?

Soluble

What is BD FACS™ Lysing Solution used for?

Scientific and industrial laboratory use. For In Vitro Diagnostic Use.

What are the hazard statements for BD FACS™ Lysing Solution?

This substance has 8 hazard statements:

  • H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
  • H314: Causes severe skin burns and eye damage.
  • H317: May cause an allergic skin reaction.
  • H335: May cause respiratory irritation.
  • H341: Suspected of causing genetic defects.
  • H350: May cause cancer.
  • H370: Causes damage to organs.
  • H373: May cause damage to organs through prolonged or repeated exposure.