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Safety Data Sheet EN

Paraformaldehyde suitable for use as excipient EMPROVE exp DAC

CAS 30525-89-4
EC 608-494-5

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Paraformaldehyde suitable for use as excipient EMPROVE exp DAC
Product Code
104005
Chemical Name
paraformaldehyde
Synonyms
Polyoxymethylene

Regulatory Identifiers

CAS Number
30525-89-4 Check regulations →
EC Number
608-494-5 Check regulations →

Identified Uses

Pharmaceutical production, Reagent for development and research

Manufacturers & Suppliers

M

Merck KGaA

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64271 Darmstadt * Germany

+49 6151 72-0

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Sol. Cat. 2 H228
Acute Tox. Cat. 4 H302
Acute Tox. Cat. 4 H332
Skin Irrit. Cat. 2 H315
Eye Dam. Cat. 1 H318
Skin Sens. Cat. 1 H317
Muta. Cat. 2 H341
Carc. Cat. 1B H350
STOT SE Cat. 3 H335

GHS Pictograms

GHS08 - Serious health hazard

GHS08

GHS02 - Flammable

GHS02

GHS07 - Health hazard

GHS07

GHS05 - Corrosive

GHS05

Hazard Statements

H228 Flammable solid.
H302 + H332 Harmful if swallowed or if inhaled
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H335 May cause respiratory irritation.
H341 Suspected of causing genetic defects.
H350 May cause cancer.

Precautionary Statements

P201 Obtain special instructions before use.
P210 Keep away from heat.
P280 Wear protective gloves.
P280 Wear eye protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Formula (CHO)n (CHO)n (Hill)

Chemical Name CAS Number Concentration Hazardous
paraformaldehyde EC: 608-494-5 30525-89-4 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

fresh air. Call in physician.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Symptoms: Dermatitis

Eye contact

rinse out with plenty of water. Immediately call in ophthalmologist.

Symptoms: Risk of serious damage to eyes.

Ingestion

immediately make victim drink water (two glasses at most). Consult a physician. Subsequently administer: activated charcoal (20 - 40 g in 10% slurry).

Symptoms: gastric pain, Nausea, Vomiting, collapse

Related Substances

Similar chemicals with comparable safety profiles

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Technical measures and appropriate working operations should be given priority over the use of personal protective equipment. See section 7.1.

Hands

full contact: Glove material: Nitrile rubber Glove thickness: 0,11 mm Break through time: - 480 min splash contact: Glove material: Nitrile rubber Glove thickness: 0,11 mm Break through time: - 480 min The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril L (full contact), KCL 741 Dermatril L (splash contact). The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types. This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Tightly fitting safety goggles

Respiratory

required when dusts are generated. Recommended Filter type: Filter P 3 (acc. to DIN 3181) for solid and liquid particles of toxic and very toxic substances The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains. Risk of explosion.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Ph
ca. 5,5 at 20 C (saturated solution)
Cloud Point
---
Partition Coefficient
No information available.
Crystallisation Point
---
Solidification Point
---
Flash Point
No information available.
Flammability
The substance or mixture is a flammable solid with the category 2.
Decomposition Temperature
No information available.
Boiling Point
No information available.
Density
1,4 g/cm3 at 20 C
Physical State Data
solid
Vapor Density
---
State Under Standard Conditions
---
Dynamic Viscosity
No information available.
Metal Corrosion
---
Solubility In Fat
---
Physical State
solid
Kinematic Viscosity
---
Colour
white
Relative Evaporation Rate
---
Solubility
---
Evaporation Rate
No information available.
Solubility In Water
at 20 C slightly soluble
Upper Explosive Limit
73 %(V)
Explosive Limits
---
Melting Point
100 - 130 C
Colour Intensity
---
Relative Density
No information available.
Odor
characteristic odour
Freezing Point
---
Bulk Density
---
Form
solid
Voc Content
---
Softening Point
---
Appearance
---
Odor Threshold
No information available.
Molecular Weight
---
Properties Status
---
Vapor Pressure
1,93 hPa at 25 C
Lower Explosive Limit
7 %(V)
Auto Ignition Temperature
No information available.
14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN 2213
Shipping Name
PARAFORMALDEHYDE
Transport Class
4.1
Packing Group
III
ADR

yes

IMDG

yes

IATA

no

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Paraformaldehyde suitable for use as excipient EMPROVE exp DAC known by?

Paraformaldehyde suitable for use as excipient EMPROVE exp DAC is also known as: Polyoxymethylene

What is the hazard signal word for Paraformaldehyde suitable for use as excipient EMPROVE exp DAC?

The signal word is danger.

What is the physical form of Paraformaldehyde suitable for use as excipient EMPROVE exp DAC?

Paraformaldehyde suitable for use as excipient EMPROVE exp DAC is a solid with white color. It has characteristic odour odor.

What is Paraformaldehyde suitable for use as excipient EMPROVE exp DAC used for?

Pharmaceutical production, Reagent for development and research

What are the hazard statements for Paraformaldehyde suitable for use as excipient EMPROVE exp DAC?

This substance has 8 hazard statements:

  • H228: Flammable solid.
  • H302 + H332: Harmful if swallowed or if inhaled
  • H315: Causes skin irritation.
  • H317: May cause an allergic skin reaction.
  • H318: Causes serious eye damage.
  • H335: May cause respiratory irritation.
  • H341: Suspected of causing genetic defects.
  • H350: May cause cancer.

What is the melting point of Paraformaldehyde suitable for use as excipient EMPROVE exp DAC?

The melting point is 100 - 130 C and the boiling point is No information available..

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