Screen your trade, customs, and legal documents for regulated chemical substances. Upload bills of lading, customs declarations, tariff schedules, SDS, and import/export paperwork to identify CAS numbers and flag compliance issues.
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| CAS Number | Substance Name | Regulatory Lists | Valid |
|---|
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| CAS Number | Substance Name | Regulatory Lists | Valid |
|---|---|---|---|
| 5989-27-5 | Limonene | ||
| 67-56-1 | Methanol | ||
| 1330-20-7 | Xylene (mixed isomers) | — | |
| 108-88-3 | Chemical substance | Regulatory list | |
| 64742-49-0 | Chemical substance | Regulatory list |
Example screening of a solvent-based paint safety data sheet
A CAS (Chemical Abstracts Service) Registry Number is a unique numerical identifier assigned to every chemical substance described in the open scientific literature. The format follows a pattern of up to 10 digits separated by hyphens (e.g., 7732-18-5 for water). CAS numbers are used globally in safety data sheets, regulatory filings under REACH and CLP, and in scientific literature to unambiguously identify substances.
Trade documents like bills of lading, customs declarations, and tariff schedules often contain chemical references that trigger regulatory obligations. Identifying these substances helps verify compliance with EU REACH, CLP, customs restrictions, and trade sanctions, and ensures proper handling, transport, and import/export obligations are met. Manual review is error-prone and time-consuming — automated screening catches CAS numbers humans miss.
The screener extracts text from your uploaded document, identifies CAS numbers using pattern matching, then validates each one with the CAS check-digit algorithm. Validated numbers are cross-referenced against chemical databases to return substance names and flag potential trade compliance concerns. The entire process takes seconds, even for multi-page documents.
CAS number identification is required across multiple regulatory and trade frameworks:
EU regulation requiring registration, evaluation, and authorisation of chemical substances. All substances manufactured or imported above 1 tonne/year must be registered with ECHA using their CAS numbers. Customs authorities verify REACH pre-registration status at EU borders.
The Classification, Labelling and Packaging regulation requires substances and mixtures to be properly classified and labelled. CAS numbers are mandatory in CLP labels, safety data sheets, and customs documentation for hazardous goods imports.
The EU Combined Nomenclature assigns tariff codes (HS/CN codes) to chemical substances for customs duties and trade statistics. CAS numbers are used to correctly classify chemicals under the right tariff heading, determining duty rates and import restrictions.
The US Toxic Substances Control Act maintains an inventory of chemical substances. Importers must file TSCA Section 13 certifications with US Customs and Border Protection, confirming CAS numbers against the TSCA inventory before entry.
The European Agreement for dangerous goods transport requires substance identification by CAS number for transport classification, packaging requirements, and documentation on bills of lading and dangerous goods declarations.
The International Maritime Dangerous Goods Code governs sea transport of hazardous chemicals. Shipping lines and customs authorities require CAS identification on bills of lading, dangerous goods manifests, and container packing certificates.
The Prior Informed Consent Regulation (EU No 649/2012) requires export notifications and consent for certain hazardous chemicals. Exporters must identify substances by CAS number in customs export declarations.
EU and US sanctions regimes restrict trade in specific chemicals used in weapons production, dual-use goods, and controlled precursors. Customs screening relies on CAS numbers to flag sanctioned substances in trade documents and export licences.
Need a full compliance check? Get a free compliance audit or book a demo for comprehensive SDS management and compliance monitoring.
Disclaimer: This screening tool is provided for informational purposes only. While the CAS number extraction and validation uses standard algorithms, results should be verified against official sources. Always consult with regulatory experts for trade compliance and customs decisions.
We screen substances against regulatory, governmental, and industry lists worldwide.
ECHA Biocidal Active Substances — Active substances for which approval has been sought under the EU Biocidal Products Regulation (EU) No 528/2012
ED List I — Substances identified as endocrine disruptors at EU level
ED List II — Substances under evaluation for endocrine disruption under an EU legislation
ED List III — Substances considered, by the evaluating National Authority, to have endocrine disrupting properties
ECHA Endocrine Disruptor assessment — Substances evaluated for endocrine-disrupting properties under REACH and CLP regulations
EU CMR Directive — Substances classified as Carcinogenic, Mutagenic or Reprotoxic (CMR Cat. 1A/1B) restricted under Directive 2004/37/EC on carcinogens and mutagens at work
EU Cosmetic Products Regulation: Prohibited Substances — Substances prohibited in cosmetic products under Annex II of Regulation (EC) No 1223/2009
ECHA Persistent Organic Pollutants (POPs) — Substances listed under Regulation (EU) 2019/1021 implementing the Stockholm Convention
EU RoHS Directive — Restriction of Hazardous Substances in electrical and electronic equipment under Directive 2011/65/EU
EU Water Framework Directive: Priority Substances — Substances posing significant risk to the aquatic environment under Directive 2000/60/EC and Directive 2013/39/EU
ECHA PBT/vPvB assessment — Substances evaluated for Persistent, Bioaccumulative and Toxic or very Persistent and very Bioaccumulative properties under REACH
ECHA REACH Annex XIV — List of substances subject to authorisation requiring specific permission for continued use (Regulation (EC) No 1907/2006)
REACH Annex XVII Restriction Entry 74 — Diisocyanates restricted under Regulation (EU) 2020/1149 amending REACH, requiring training for industrial and professional use of substances containing diisocyanates at concentration >= 0.1% by weight
ECHA REACH Annex XVII — Restrictions on the manufacture, placing on the market and use of certain dangerous substances, mixtures and articles (Regulation (EC) No 1907/2006)
ECHA authorisation process — Substances under evaluation for potential REACH Annex XIV inclusion
ECHA restriction process — Substances under evaluation for potential REACH Annex XVII restriction proposals
ECHA Candidate List of Substances of Very High Concern (SVHC) for Authorisation under REACH Article 59
ECHA SVHC identification — Substances under evaluation for Candidate List inclusion as Substances of Very High Concern
California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986) — List of chemicals known to the State of California to cause cancer or reproductive toxicity
Canadian Environmental Protection Act (CEPA) — Substances assessed as toxic under the Canadian Environmental Protection Act, 1999
EPA/OECD Comprehensive Global Database of Per- and Polyfluoroalkyl Substances (PFAS) — Consolidated inventory of PFAS identified from various national and international lists and scientific literature
GDA — German Hazardous Substances Ordinance (Gefahrstoffdatenbank) list of restricted substances
German Federal Environment Agency (UBA) — Substances identified by the Umweltbundesamt as environmentally hazardous or requiring regulatory action
IFA GESTIS International Limit Values (ILV) — Occupational exposure limits for chemical agents in the workplace, maintained by the Institut für Arbeitsschutz der DGUV (Germany)
KEMI PRIO Phase-Out Substances — Swedish Chemicals Agency list of substances with properties of very high concern that should be phased out
Massachusetts Toxics Use Reduction Act (TURA) — Substances designated as toxic or hazardous under Massachusetts state toxics use reduction program
RIVM ZZS (Zeer Zorgwekkende Stoffen) — Dutch list of Substances of Very High Concern maintained by the National Institute for Public Health and the Environment (RIVM), based on REACH SVHC criteria and CMR/PBT/ED properties
UBA PMT/vPvM List — Persistent, Mobile and Toxic (PMT) and very Persistent and very Mobile (vPvM) substances assessed under REACH by the German Environment Agency (Umweltbundesamt)
UBA Prioritised PMT/vPvM Substances — Persistent, Mobile and Toxic (PMT) and very Persistent and very Mobile (vPvM) substances assessed by the German Environment Agency
US EPA — Substances regulated or restricted under United States Environmental Protection Agency programs
OSPAR Chemicals for Priority Action — Substances prioritised by the OSPAR Commission for cessation of discharges, emissions and losses to the marine environment
OSPAR List of Chemicals of Possible Concern — Substances identified by the OSPAR Commission as potentially hazardous to the marine environment of the North-East Atlantic
Stockholm Convention on Persistent Organic Pollutants (POPs) — Substances listed for elimination, restriction or reduction under the international Stockholm Convention treaty
Global Automotive Declarable Substance List (GADSL) — Industry-wide list of declarable and prohibited substances in automotive manufacturing
OEKO-TEX Standard 100 — Limit values for harmful substances in textiles certified under the international OEKO-TEX testing and certification system
ZDHC Manufacturing Restricted Substances List (MRSL) — Substances restricted from intentional use in facilities processing textile and footwear materials
Bluesign System Substances List — Substances restricted or banned under the Bluesign chemical management system for sustainable textile production
Boots Restricted Substances — Chemicals restricted from use in Boots-branded consumer products
Dell Restricted Substances — Chemicals restricted from use in Dell electronic products and packaging
H&M Chemical Restrictions — Substances restricted from use in H&M Group textile and consumer products
Nokia Restricted Substances — Chemicals restricted from use in Nokia electronic products
SC Johnson GreenList — Proprietary substance classification system rating raw materials by environmental and health profile
Vestas Blacklist — Substances banned from use in Vestas wind turbine manufacturing
Volvo Black List — Substances prohibited from use in Volvo vehicles and manufacturing processes
Volvo Grey List — Substances subject to restricted use in Volvo vehicles, targeted for phase-out
ChemSec SIN List — Substitute It Now list of substances identified by the International Chemical Secretariat as meeting SVHC criteria under REACH
ETUI Hazardous Medicinal Products (HMP) — List of hazardous medicinal products identified by the European Trade Union Institute for occupational health protection
Kühlschmierstoffe VKIS-VSI-IGM-BGHM — German metalworking fluids restricted substances list maintained jointly by industry and trade union organisations
Trade Union Priority List — Substances prioritised by European trade unions for workplace exposure reduction and substitution
