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Safety Data Sheet EN

Lidocaine Hydrochloride Injection

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Lidocaine Hydrochloride Injection
Synonyms
Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-monohydrochloride; 2',6'-Acetoxylidide, 2-(diethylamino)-, hydrochloride

Regulatory Identifiers

CAS Number
N/A

Manufacturers & Suppliers

H

Hospira, Inc.

manufacturer

275 North Field Drive, Lake Forest, Illinois 60045, USA

224 212-2000

Emergency Contacts

CHEMTREC

800-424-9300

CHEMTREC

1-703-527-3887

CHEMTREC

61-290372994

CHEMTREC

44-870-8200418

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

STOT RE Cat. 2

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H373 May cause damage to organs through prolonged or repeated exposures

Precautionary Statements

P261 Do not breathe vapor or spray
P264 Wash hands thoroughly after handling
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists, get medical attention.
P314 Get medical attention if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture

Non-hazardous ingredients include Water for Injection; some preparation may contain up to 7.5% dextrose. Hazardous ingredients present at less than 1% may include sodium chloride; sodium hydroxide and/or hydrochloric acid are used to adjust the pH. Multiple-dose vials contain 0.1% of methylparaben added as a preservative.

Chemical Name CAS Number Concentration Hazardous
Lidocaine Hydrochloride 73-78-9 5% Yes
Water for Injection --- --- No
Dextrose --- 7.5% No
Sodium Chloride --- 1% Yes
Sodium Hydroxide --- --- Yes
Hydrochloric Acid --- --- Yes
Methylparaben --- 0.1% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove from source of exposure. If signs of toxicity occur, seek medical attention. Provide symptomatic/supportive care as necessary.

Skin contact

Remove from source of exposure. Flush with copious amounts of water. If irritation persists or signs of toxicity occur, seek medical attention. Provide symptomatic/supportive care as necessary.

Eye contact

Remove from source of exposure. Flush with copious amounts of water. If irritation persists or signs of toxicity occur, seek medical attention. Provide symptomatic/supportive care as necessary.

Ingestion

Remove from source of exposure. If signs of toxicity occur, seek medical attention. Provide symptomatic/supportive care as necessary.

Immediate Medical Attention

If irritation persists or signs of toxicity occur, seek medical attention.

Medical Treatment

Provide symptomatic/supportive care as necessary.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

carbon dioxide, dry chemical extinguishing powder or foam

Specific hazards

None anticipated from this aqueous product.

Instructions

No special provisions required beyond normal firefighting equipment

Firefighter Protection

flame and chemical resistant clothing and self contained breathing apparatus

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Isolate area around spill.

Cleanup methods

Absorb any liquid with suitable material and clean affected area with soap and water.

Materials: suitable material, soap and water

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

No special handling required under conditions of normal product use.

Storage

No special storage required for hazard control. For product protection, follow storage recommendations noted on the product case label, the primary container label, or the product insert.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Engineering controls are normally not needed during the normal use of this product.

Hands

If skin contact with the product formulation is likely, the use of latex or nitrile gloves is recommended.

Eyes

Eye protection is normally not required during intended product use. However, if eye contact is likely to occur, the use of chemical safety goggles (as a minimum) is recommended.

Respiratory

Respiratory protection is normally not needed during intended product use. However, if the generation of aerosols is likely, and engineering controls are not considered adequate to control potential airborne exposures, the use of an approved air-purifying respirator with a HEPA cartridge (N95 or equivalent) is recommended under conditions where airborne aerosol concentrations are not expected to be excessive. For uncontrolled release events, or if exposure levels are not known, provide respirators that offer a high protection factor such as a powered air purifying respirator or supplied air. A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements must be followed whenever workplace conditions require respirator use. Personnel who wear respirators should be fit tested and approved for respirator use as required.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
Clear, colorless liquid
Bulk Density
---
Solidification Point
---
Ph
Between 5.0 and 7.0
Vapor Density
---
Solubility
Very soluble in water and in alcohol; soluble in chloroform; insoluble in ether.
Lower Explosive Limit
---
Partition Coefficient
---
Odor
---
Density
---
Colour Intensity
---
Auto Ignition Temperature
---
Flammability
---
Relative Evaporation Rate
---
Softening Point
---
Properties Status
---
Kinematic Viscosity
---
Form
---
Vapor Pressure
---
Molecular Weight
---
Physical State Data
liquid
Odor Threshold
---
Solubility In Fat
---
Voc Content
---
Upper Explosive Limit
---
Boiling Point
---
Explosive Limits
---
State Under Standard Conditions
---
Cloud Point
---
Appearance
Clear, colorless liquid
Melting Point
---
Colour
colorless
Flash Point
---
Metal Corrosion
---
Crystallisation Point
---
Dynamic Viscosity
---
Relative Density
---
Freezing Point
---
Solubility In Water
Very soluble in water
Evaporation Rate
---
Decomposition Temperature
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under standard use and storage conditions.

Reactivity

Not determined.

Hazardous reactions

Not determined. Hazardous polymerization: Not anticipated to occur with this product.

Avoid

Not determined

Incompatible

Strongly alkaline conditions. Methyl vinyl ether; zinc.

Decomposition

Not determined. During thermal decomposition, it may be possible to generate irritating vapors and/or toxic fumes of carbon oxides (COx), nitrogen oxides (NOx), and hydrogen chloride.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

All waste materials must be properly characterized. Further, disposal should be performed in accordance with the federal, state or local regulatory requirements.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Medicinal products as defined in Directive 2001/83/EC are exempt from GHS/CLP and EU Dangerous Preparations Directive requirements in their finished state.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Lidocaine Hydrochloride Injection known by?

Lidocaine Hydrochloride Injection is also known as: Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-monohydrochloride; 2',6'-Acetoxylidide, 2-(diethylamino)-, hydrochloride

What is the hazard signal word for Lidocaine Hydrochloride Injection?

The signal word is warning.

What is the physical form of Lidocaine Hydrochloride Injection?

Lidocaine Hydrochloride Injection is a clear, colorless liquid appearing as clear, colorless liquid with colorless color.

What is the solubility of Lidocaine Hydrochloride Injection?

Very soluble in water and in alcohol; soluble in chloroform; insoluble in ether.

What are the hazard statements for Lidocaine Hydrochloride Injection?

This substance has 1 hazard statement:

  • H373: May cause damage to organs through prolonged or repeated exposures