Chemical Product Identification & Regulatory Data
Official chemical identifiers, CAS numbers, and regulatory compliance information
Basic Product Information
Regulatory Identifiers
Chemical Abstracts Service registry number - unique identifier for chemical substances
Uses Information
Overview
Hexamethylphosphoramide is a form: liquid substance commonly used laboratory chemicals, synthesis of substances.
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GHS Hazard Classification & Safety Warnings
Globally Harmonized System (GHS) hazard pictograms, signal words, and safety classifications
Classification Status
Signal Word
Hazard Classifications
GHS Hazard Pictograms & Safety Symbols
GHS08
GHS (Globally Harmonized System) pictograms indicate specific chemical hazard categories and safety precautions
Hazard Statements
- H340: May cause genetic defects.
- H350: May cause cancer.
Precautionary Statements
- P201: Obtain special instructions before use.
- P202: Do not handle until all safety precautions have been read and understood.
- P280: Wear protective gloves/ protective clothing/ eye protection/ face protection.
- P308+P313: IF exposed or concerned: Get medical advice/ attention.
- P405: Store locked up.
- P501: Dispose of contents/ container to an approved waste disposal plant.
Chemical Manufacturers & Supply Chain
Authorized suppliers, manufacturers, and distribution network information
Sigma-Aldrich
manufacturer
3050 Spruce Street SAINT LOUIS MO 63103 USA
US
+1 800-325-5832
+1 800-325-5052
24/7 Emergency Response & Poison Control
Critical emergency contact numbers for chemical spills, exposure incidents, and medical emergencies
CHEMTREC
+1-703-527-3887
US
Chemical Composition & Hazardous Ingredients
Detailed component analysis, concentration ranges, and hazardous substance identification
Product Type
substanceGeneral Composition
HMPA (Hexamethylphosphoric acid triamide) with a chemical formula of C6H18N3OP.
Chemical Components & Hazardous Substances
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Hexamethylphosphoric triamide EC: 211-653-8 | 680-31-9 | 90-100% | ⚠️ Hazardous |
Emergency First Aid Measures
Critical first aid procedures for chemical exposure incidents and medical emergencies
🫁 Inhalation Exposure
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
🖐️ Skin Contact
Wash off with soap and plenty of water. Consult a physician.
👁️ Eye Contact
Flush eyes with water as a precaution.
🍽️ Ingestion/Swallowing
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Fire Fighting Measures & Emergency Response
Fire suppression methods, extinguishing media, and firefighting safety procedures
✅ Suitable Extinguishing Media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
🔥 Fire Fighting Instructions
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental Release Measures & Spill Response
Emergency spill cleanup procedures, containment methods, and environmental protection
🚨 Emergency Procedures
Evacuate personnel to safe areas.
🌍 Environmental Precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
🧹 Cleanup Methods
Keep in suitable, closed containers for disposal.
Related Chemical Substances & Alternative Products
Similar chemicals with comparable safety profiles and industrial applications
Technical Specifications & Material Properties
Physical state, chemical properties, melting point, boiling point, and material characteristics
Safe Handling & Storage Procedures
Industrial handling precautions, storage conditions, and workplace safety requirements
⚠️ Handling Precautions
• Avoid inhalation of vapour or mist.
• For precautions see section 2.
• 2.
🏪 Storage Conditions
• Keep container tightly closed in a dry and well-ventilated place.
• Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Exposure Controls & Personal Protective Equipment (PPE)
Occupational exposure limits, engineering controls, and required safety equipment
🏭 Engineering Controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
🧤 Hand Protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Full contact Material: butyl-rubber Minimum layer thickness: 0.3 mm Break through time: 480 min Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.2 mm Break through time: 30 min Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail [email protected], test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
👁️ Eye Protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
😷 Respiratory Protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
🦺 Skin/Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
🌍 Environmental Exposure Controls
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Chemical Stability & Reactivity Data
Chemical stability, hazardous reactions, and incompatible materials information
✅ Chemical Stability
Stable under recommended storage conditions.
🧪 Incompatible Materials
Strong oxidizing agents, Strong acids
💨 Hazardous Decomposition Products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Oxides of phosphorus, Thermal decomposition may produce toxic fumes of phosphorus oxides and/or phosphine Other decomposition products - No data available
Ecological Information & Environmental Impact
Environmental toxicity, biodegradation, bioaccumulation, and ecological effects data
🌱 Toxicity
🌱 Persistence and degradability
🌱 Bioaccumulative potential
🌱 Mobility in soil
🌱 Results of PBT and vPvB assessment
🌱 Endocrine disrupting properties
Waste Disposal & Treatment Methods
Waste disposal procedures, treatment methods, and regulatory compliance requirements
♻️ Waste Treatment Methods
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Transportation & Shipping Information
UN numbers, shipping names, transport classes, and regulatory transport requirements
🏷️ UN Number
3082
📦 Proper Shipping Name
Environmentally hazardous substance, liquid, n.o.s. (Hexamethylphosphoric triamide)
⚠️ Transport Hazard Class
9
📋 Packing Group
III
Chemical Safety FAQ & Common Questions
Most frequently asked questions about safety, handling, storage, and regulatory compliance
What is the hazard signal word for Hexamethylphosphoramide?
The signal word for this substance is "danger".
What is the physical form of Hexamethylphosphoramide?
Hexamethylphosphoramide is a liquid appearing as form: liquid . It has no data available odor.
What is the solubility of Hexamethylphosphoramide?
No data available
What is Hexamethylphosphoramide used for?
Laboratory chemicals, Synthesis of substances
What are the hazard statements for Hexamethylphosphoramide?
This substance has 2 hazard statements: H340: May cause genetic defects. H350: May cause cancer.
What is the melting point of Hexamethylphosphoramide?
The melting point is 7 ℃ (45 °F) and the boiling point is 230 - 232 °℃ (446 - 450 °F) at 987 hPa (740 mmHg).