Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Hexamethylphosphoramide
- Product Code
- H11602
- Chemical Name
- Hexamethylphosphoramide
Regulatory Identifiers
- CAS Number
- 680-31-9 Check regulations →
Identified Uses
Laboratory chemicals, Synthesis of substances
Manufacturers & Suppliers
Sigma-Aldrich
manufacturer
3050 Spruce Street, SAINT LOUIS MO 63103, USA
+1 800-325-5832
Emergency Contacts
CHEMTREC
+1-703-527-3887
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS08
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
HMPA (Hexamethylphosphoric acid triamide) with a chemical formula of C6H18N3OP.
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Hexamethylphosphoric triamide EC: 211-653-8 | 680-31-9 | 90 - 100% | Yes |
First Aid Measures
Emergency procedures for chemical exposure incidents
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
Wash off with soap and plenty of water. Consult a physician.
Flush eyes with water as a precaution.
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Immediate Medical Attention
No data available
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Firefighter Protection
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Evacuate personnel to safe areas.
Prevent further leakage or spillage if safe to do so.
Soak up with inert absorbent material
Materials: inert absorbent material
Related Products
Similar products with comparable safety profiles
Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Avoid inhalation of vapour or mist.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Air and moisture sensitive. Handle and store under inert gas.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Handle in accordance with good industrial hygiene and safety practice.
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Full contact: Material: butyl-rubber, Minimum layer thickness: 0.3 mm, Break through time: 480 min, Material tested: Butoject® (KCL 897 / Aldrich Z677647, Size M). Splash contact: Material: Nitrile rubber, Minimum layer thickness: 0.2 mm, Break through time: 30 min, Material tested: Dermatril® P (KCL 743 / Aldrich Z677388, Size M). Test method: EN374.
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
Stable under recommended storage conditions.
No data available
No data available
No data available
Strong oxidizing agents, Strong acids
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Oxides of phosphorus, Thermal decomposition may produce toxic fumes of phosphorus oxides and/or phosphine. Other decomposition products - No data available
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- 3082
- Shipping Name
- Environmentally hazardous substance, liquid, n.o.s. (Hexamethylphosphoric triamide)
- Transport Class
- 9
- Packing Group
- III
Regulatory Information
Chemical regulations, safety assessments, and compliance status
Frequently Asked Questions
Common questions about safety, handling, and properties
What is the hazard signal word for Hexamethylphosphoramide?
The signal word is danger.
What is the physical form of Hexamethylphosphoramide?
Hexamethylphosphoramide is a liquid appearing as form: liquid . It has no data available odor.
What is the solubility of Hexamethylphosphoramide?
No data available
What is Hexamethylphosphoramide used for?
Laboratory chemicals, Synthesis of substances
What are the hazard statements for Hexamethylphosphoramide?
This substance has 2 hazard statements:
- H340: May cause genetic defects.
- H350: May cause cancer.
What is the melting point of Hexamethylphosphoramide?
The melting point is 7 °C (45 °F) and the boiling point is 230 - 232 °C (446 - 450 °F).