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Safety Data Sheet EN

Rapamycin from Streptomyces hygroscopicus

CAS 53123-88-9

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Rapamycin from Streptomyces hygroscopicus
Product Code
R0395

Regulatory Identifiers

CAS Number
53123-88-9 Check regulations →
REACH No.
A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

M

Merck Life Science BV/SRL

manufacturer

Brusselsesteenweg 288, B-3090 OVERIJSE

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Carc. Cat. 2 H351
Repr. Cat. 2 H361fd

GHS Pictograms

GHS08 - Serious health hazard

GHS08

Hazard Statements

H351 Suspected of causing cancer.
H361fd Suspected of damaging fertility. Suspected of damaging the unborn child.

Precautionary Statements

P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Rapamycin EC: 610-965-5 53123-88-9 100% Yes

Notes

For the full text of the H-Statements mentioned in this Section, see Section 16.

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention

Call in physician. Call in ophthalmologist.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Nitrogen oxides (NOx), Combustible. Development of hazardous combustion gases or vapours possible in the event of fire. Risk of dust explosion.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains.

Cleanup methods

Take up dry. Clean up affected area.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture.

Storage

Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized persons.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3. The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

protective clothing

Environmental

Do not let product enter drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Solubility
insoluble
Vapor Density
No data available
Freezing Point
---
Melting Point
183 - 185 °C
Flash Point
No data available
Form
powder
Molecular Weight
---
Odor Threshold
No data available
Lower Explosive Limit
No data available
Metal Corrosion
---
Auto Ignition Temperature
No data available
Properties Status
---
Solidification Point
---
Upper Explosive Limit
No data available
Voc Content
---
Density
---
Appearance
Form: powder, Color: clear
Vapor Pressure
No data available
Boiling Point
973,02 °C at 1.013,3 hPa
Partition Coefficient
No data available
Odor
No data available
Physical State
powder
Dynamic Viscosity
No data available
Bulk Density
---
Softening Point
---
Relative Evaporation Rate
---
Explosive Limits
---
State Under Standard Conditions
---
Evaporation Rate
No data available
Flammability
No data available
Cloud Point
---
Physical State Data
solid
Decomposition Temperature
No data available
Colour Intensity
---
Relative Density
No data available
Solubility In Water
insoluble
Kinematic Viscosity
No data available
Solubility In Fat
---
Colour
clear
Crystallisation Point
---
Ph
No data available
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous reactions

No data available

Avoid

no information available

Incompatible

Strong oxidizing agents

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

Disposal

See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

Shipping Name
Not dangerous goods
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Rapamycin from Streptomyces hygroscopicus?

The signal word is warning.

What is the physical form of Rapamycin from Streptomyces hygroscopicus?

Rapamycin from Streptomyces hygroscopicus is a powder appearing as form: powder, color: clear with clear color. It has no data available odor.

What is the solubility of Rapamycin from Streptomyces hygroscopicus?

insoluble

What is Rapamycin from Streptomyces hygroscopicus used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Rapamycin from Streptomyces hygroscopicus?

This substance has 2 hazard statements:

  • H351: Suspected of causing cancer.
  • H361fd: Suspected of damaging fertility. Suspected of damaging the unborn child.

What is the melting point of Rapamycin from Streptomyces hygroscopicus?

The melting point is 183 - 185 °C and the boiling point is 973,02 °C at 1.013,3 hPa.