NextSDS Logo
Ra

Rapamycin from Streptomyces hygroscopicus

WARNING powder SDS/MSDS
Chemical Identity

Product Identification & Regulatory Data

Official chemical identifiers, CAS numbers, and regulatory compliance information

Basic Product Information

Product Name
Rapamycin from Streptomyces hygroscopicus
Product Code
R0395
Chemical Name
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
Synonyms
Sirolimus

Regulatory Identifiers

CAS Number

Chemical Abstracts Service registry number - unique identifier for chemical substances

EC Number

European Community number - used for regulatory compliance in EU/EEA

Uses Information

Identified Uses
Laboratory chemicals, Manufacture of substances

Overview

Rapamycin from Streptomyces hygroscopicus (CAS: 53123-88-9 ) is a form: powder, color: clear substance commonly used laboratory chemicals, manufacture of substances.

Manage Your Safety Data Sheets

Organize and access your chemical safety data with ease.

Safety Classification

GHS Hazard Classification & Safety Warnings

Globally Harmonized System (GHS) hazard pictograms, signal words, and safety classifications

Classification Status

Classified

Signal Word

warning (Warning)

Hazard Classifications

Carc. Category 2 H351
Repr. Category 2 H361

GHS Hazard Pictograms & Safety Symbols

GHS08 GHS Hazard Pictogram: Serious health hazard - Carcinogenic, mutagenic, or toxic to organs

GHS08

GHS (Globally Harmonized System) pictograms indicate specific chemical hazard categories and safety precautions

Hazard Statements

  • H351: Suspected of causing cancer.
  • H361: Suspected of damaging fertility. Suspected of damaging the unborn child.

Precautionary Statements

  • P201: Obtain special instructions before use.
  • P202: Do not handle until all safety precautions have been read and understood.
  • P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
  • P308 + P313: IF exposed or concerned: Get medical advice/ attention.
  • P405: Store locked up.
  • P501: Dispose of contents/ container to an approved waste disposal plant.
Supply Chain

Manufacturers & Suppliers

Authorized suppliers, manufacturers, and distribution network information

Merck Life Science BV/SRL

national supplier

Brusselsesteenweg 288 B-3090 OVERIJSE

BE

+32 (0)3 899-1301

+32 (0)3 899-1311

Emergency

24/7 Emergency Response

Critical emergency contact numbers for chemical spills, exposure incidents, and medical emergencies

CHEMTREC

+(32) 28 083237

BE

Anti-poison centre

070 245245

BE

Composition

Chemical Composition & Hazardous Ingredients

Detailed component analysis, concentration ranges, and hazardous substance identification

Product Type

substance

Chemical Components & Hazardous Substances

Chemical Name CAS Number Concentration Hazardous
Rapamycin
EC: 610-965-5
53123-88-9 100% Hazardous

Composition Notes

For the full text of the H-Statements mentioned in this Section, see Section 16.

First Aid

Emergency First Aid Measures

Critical first aid procedures for chemical exposure incidents and medical emergencies

Inhalation Exposure

After inhalation: fresh air. Call in physician.

Skin Contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye Contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion/Swallowing

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention Required

No data available

Medical Treatment

No data available

Alternatives

Related Chemical Substances & Alternative Products

Similar chemicals with comparable safety profiles and industrial applications

Section 9

Technical Specifications & Material Properties

Physical state, chemical properties, melting point, boiling point, and material characteristics

Form
powder
Physical State Data
solid
Solubility In Water
insoluble
State Under Standard Conditions
Not available
Appearance
Form: powder, Color: clear
Metal Corrosion
Not available
Molecular Weight
Not available
Odor
No data available
Colour
clear
Properties Status
Not available
Relative Density
No data available
Softening Point
Not available
Bulk Density
Not available
Boiling Point
973,02 °C at 1.013,3 hPa
Critical Property
Physical State
powder
Critical Property
Ph
No data available
Melting Point
183 - 185 °C
Critical Property
Voc Content
Not available
Density
Not available
Kinematic Viscosity
No data available
Solubility
insoluble
Freezing Point
Not available
Upper Explosive Limit
No data available
Flammability
No data available
Flash Point
No data available
Critical Property
Lower Explosive Limit
No data available
Vapor Density
No data available
Decomposition Temperature
No data available
Vapor Pressure
No data available
Crystallisation Point
Not available
Auto Ignition Temperature
No data available
Explosive Limits
Not available
Evaporation Rate
No data available
Partition Coefficient
No data available
Odor Threshold
No data available
Dynamic Viscosity
No data available
Cloud Point
Not available
Colour Intensity
Not available
Relative Evaporation Rate
Not available
Solubility In Fat
Not available
Solidification Point
Not available
Section 8

Exposure Controls & Personal Protective Equipment

Occupational exposure limits, engineering controls, and required safety equipment

Eye Protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory Protection

required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body Protection

protective clothing

Environmental Exposure Controls

Do not let product enter drains.

Section 10

Chemical Stability & Reactivity Data

Chemical stability, hazardous reactions, and incompatible materials information

Chemical Stability

The product is chemically stable under standard ambient conditions (room temperature) .

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Hazardous Reactions

No data available

Conditions to Avoid

no information available

Incompatible Materials

Strong oxidizing agents

Hazardous Decomposition Products

In the event of fire: see section 5

Section 14

Transportation & Shipping Information

UN numbers, shipping names, transport classes, and regulatory transport requirements

Proper Shipping Name

Not dangerous goods

FAQ

Chemical Safety FAQ & Common Questions

Most frequently asked questions about safety, handling, storage, and regulatory compliance

What other names is Rapamycin from Streptomyces hygroscopicus known by?

Rapamycin from Streptomyces hygroscopicus is also known as: Sirolimus

What is the hazard signal word for Rapamycin from Streptomyces hygroscopicus?

The signal word for this substance is "warning".

What is the physical form of Rapamycin from Streptomyces hygroscopicus?

Rapamycin from Streptomyces hygroscopicus is a powder appearing as form: powder, color: clear with clear color. It has no data available odor.

What is the solubility of Rapamycin from Streptomyces hygroscopicus?

insoluble

What is Rapamycin from Streptomyces hygroscopicus used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for Rapamycin from Streptomyces hygroscopicus?

This substance has 2 hazard statements: H351: Suspected of causing cancer. H361: Suspected of damaging fertility. Suspected of damaging the unborn child.

What is the melting point of Rapamycin from Streptomyces hygroscopicus?

The melting point is 183 - 185 °C and the boiling point is 973,02 °C at 1.013,3 hPa.