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Safety Data Sheet EN

1,2-Propylene oxide for synthesis

CAS 75-56-9

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
1,2-Propylene oxide for synthesis
Product Code
8.07027
Chemical Name
1,2-Propylene oxide

Regulatory Identifiers

CAS Number
75-56-9 Check regulations →
REACH No.
01-2119480483-35-XXXX

Identified Uses

Chemical for synthesis

Manufacturers & Suppliers

M

Merck Life Science UK Limited

manufacturer

New Road, The Old Brickyard, GILLINGHAM, Dorset, SP8 4XT, UNITED KINGDOM

+44 (0)1747 833-000

Emergency Contacts

CHEMTREC

+44 (0)870 8200418

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 1 H224
Acute Tox. Cat. 4 H302
Acute Tox. Cat. 3 H331
Acute Tox. Cat. 3 H311
Eye Irrit. Cat. 2 H319
Muta. Cat. 1B H340
Carc. Cat. 1B H350
STOT SE Cat. 3 H335

GHS Pictograms

GHS02 - Flammable

GHS02

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H224 Extremely flammable liquid and vapour.
H302 Harmful if swallowed.
H311 + H331 Toxic in contact with skin or if inhaled.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H340 May cause genetic defects.
H350 May cause cancer.

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
propylene oxide EC: 200-879-2 75-56-9 100% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Immediate Medical Attention

Immediately call in physician.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Carbon dioxide (CO2) Foam Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Combustible. Pay attention to flashback. Vapours are heavier than air and may spread along floors. Forms explosive mixtures with air at ambient temperatures.

Instructions

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains. Risk of explosion.

Cleanup methods

Take up carefully with liquid-absorbent material (e.g. Chemizorb®). Clean up affected area.

Materials: liquid-absorbent material (e.g. Chemizorb®)

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Storage

Keep container tightly closed in a dry and well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons. Recommended storage temperature see product label.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Material: butyl-rubber, Minimum layer thickness: 0.7 mm, Break through time: 30 min, Material tested: Butoject® (KCL 898)

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Respiratory

required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type AX. The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

Flame retardant antistatic protective clothing.

Environmental

Do not let product enter drains. Risk of explosion.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Relative Density
0.83 at 20 ℃ - Regulation (EC) No. 440/2008, Annex, A.3
Flash Point
-38 ℃ - Equilibrium method - closed cup
Colour
colourless
Decomposition Temperature
No data available
Properties Status
---
Vapor Density
---
Bulk Density
---
Lower Explosive Limit
Lower explosion limit: 1.9 %(V)
Partition Coefficient
log Pow: < 1 at 20 ℃ - Bioaccumulation is not expected.
Explosive Limits
---
Relative Evaporation Rate
---
Solubility In Fat
---
Solubility
---
Flammability
No data available
Form
---
Vapor Pressure
2,028.5 hPa at 55 ℃
State Under Standard Conditions
---
Colour Intensity
---
Odor Threshold
---
Solidification Point
---
Freezing Point
---
Metal Corrosion
---
Physical State
liquid
Cloud Point
---
Upper Explosive Limit
Upper explosion limit: 36 - 45 %(V)
Solubility In Water
425 g/l at 20 ℃ - OECD Test Guideline 105
Dynamic Viscosity
0.32 mPa.s at 20 ℃
Auto Ignition Temperature
> 400 °℃ at 1,005 - 1,018 hPa - Tested according to Directive 92/69/EEC.
Physical State Data
liquid
Melting Point
Melting point: - 112 ℃ at ca.1,013 hPa - (ECHA)
Softening Point
---
Odor
sweet, ether-like
Kinematic Viscosity
0.44 mm2/s at 0 ℃ - OECD Test Guideline 1140.37 mm2/s at 20 ℃ - OECD Test Guideline 114
Ph
No data available
Appearance
---
Crystallisation Point
---
Voc Content
---
Evaporation Rate
---
Density
0.83 g/cm3 at 20 ℃ - OECD Test Guideline 109
Molecular Weight
---
Boiling Point
34.3 ºC at 1,013 hPa
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature) .

Reactivity

Vapours may form explosive mixture with air.

Hazardous reactions

Risk of ignition or formation of inflammable gases or vapours with: Hydrogen fluoride, Oxidizing agents, Nitric acid. Risk of explosion with: polymerisation initiators, Oxygen. Exothermic reaction with: Strong oxidizing agents, Ammonia, halogens, alkali hydroxides, polymerisation, alkalines, Amines, metallic oxides, metallic chlorides, chlorosulfonic acid, Hydrogen chloride gas, fuming sulfuric acid, aluminium chloride, acids.

Avoid

Warming

Incompatible

Hydrogen fluoride, Oxidizing agents, Nitric acid, polymerisation initiators, Oxygen, Strong oxidizing agents, Ammonia, halogens, alkali hydroxides, alkalines, Amines, metallic oxides, metallic chlorides, chlorosulfonic acid, Hydrogen chloride gas, fuming sulfuric acid, aluminium chloride, acids.

Decomposition

Peroxides. In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
1280
Shipping Name
PROPYLENE OXIDE
Transport Class
3
Packing Group
I
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 1,2-Propylene oxide for synthesis?

The signal word is danger.

What is the physical form of 1,2-Propylene oxide for synthesis?

1,2-Propylene oxide for synthesis is a liquid with colourless color. It has sweet, ether-like odor.

What is 1,2-Propylene oxide for synthesis used for?

Chemical for synthesis

What are the hazard statements for 1,2-Propylene oxide for synthesis?

This substance has 7 hazard statements:

  • H224: Extremely flammable liquid and vapour.
  • H302: Harmful if swallowed.
  • H311 + H331: Toxic in contact with skin or if inhaled.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.
  • H340: May cause genetic defects.
  • H350: May cause cancer.

What is the melting point of 1,2-Propylene oxide for synthesis?

The melting point is Melting point: - 112 ℃ at ca.1,013 hPa - (ECHA) and the boiling point is 34.3 ºC at 1,013 hPa.