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Safety Data Sheet EN

Chloroform

CAS 67-66-3
EC 200-663-8

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Chloroform
Product Code
C/4920/08, C/4920/15, C/4920/17, C/4920/21, C/4920/25, C/4920/27 C/4920/PB17, C/4920/PC21, C/4920/21RSS, C/4920/24RSS, C/4920/25RSS, C/4920/34RSS, C/4920/27RSS
Chemical Name
Chloroform
Synonyms
Methane trichloride; Methenyl trichloride; Formyl trichloride

Regulatory Identifiers

CAS Number
67-66-3 Check regulations →
EC Number
200-663-8 Check regulations →
REACH No.
01-2119486657-20

Identified Uses

Laboratory chemicals. Sector of use: SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites. Product category: PC21 - Laboratory chemicals. Process categories: PROC15 - Use as a laboratory reagent. Environmental release category: ERC6a - Industrial use resulting in manufacture of another substance (use of intermediates)

Uses advised against

All other uses

Manufacturers & Suppliers

F

Fisher Scientific UK

national supplier

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

T

Thermo Fisher Scientific

national supplier

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

Emergency Contacts

Fisher Scientific UK

01509 231166

Chemtrec US

(800) 424-9300

Chemtrec EU

001-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302
Acute Tox. Cat. 3 H331
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
Carc. Cat. 2 H351
Repr. Cat. 2 H361d
STOT SE Cat. 3 H336
STOT RE Cat. 1 H372

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H331 Toxic if inhaled
H336 May cause drowsiness or dizziness
H351 Suspected of causing cancer
H361d Suspected of damaging the unborn child
H372 Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 IF ON SKIN: Wash with plenty of soap and water
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P311 Call a POISON CENTER or doctor/physician

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Chloroform EC: 200-663-8 67-66-3 99% Yes
1-Pentene EC: 203-694-5 109-67-1 0.01% Yes

REACH registration number: 01-2119486657-20

Notes

Amylene is used as a stabilizer, but there is evidence that it may not prevent phosgene generation. Chloroform stabilized with amylene should be tested for phosgene content.

04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required.

Symptoms: Difficulty in breathing. Symptoms of overexposure are dizziness, headache, tiredness, nausea, unconsciousness, cessation of breathing.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Ingestion

Do NOT induce vomiting. Call a physician or poison control center immediately.

Immediate Medical Attention

Immediate medical attention is required.

Medical Treatment

Treat symptomatically. Signs of overdose include stupor and respiratory depression.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.

Unsuitable media

No information available.

Specific hazards

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Instructions

Thermal decomposition can lead to release of irritating gases and vapors.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment as required. Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas.

Environmental

Should not be released into the environment.

Cleanup methods

Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.

Materials: inert absorbent material

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance.

Storage

Keep containers tightly closed in a dry, cool and well-ventilated place. Protect from direct sunlight. Store under an inert atmosphere. Protect from moisture.

Hygiene

Handle in accordance with good industrial hygiene and safety practice.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Use only under a chemical fume hood. Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Viton (R) (Breakthrough time: >480 minutes, Level 6, EN 374), Neoprene (Breakthrough time: <25 minutes, thickness: 0.45 mm), Butyl rubber (Breakthrough time: <15 minutes, thickness: 0.35 mm).

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator. Recommended Filter type: low boiling organic solvent Type AX Brown conforming to EN371. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator. Recommended half mask: Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141.

Skin/Body

Long sleeved clothing.

Environmental

Prevent product from entering drains.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Melting Point
-63 °C / -81.4 °F
Bulk Density
Not applicable
Solubility In Water
8 g/L (20°C)
Kinematic Viscosity
---
Ph
No information available
Flash Point
No information available
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Physical State
Liquid
Odor Threshold
No data available
Decomposition Temperature
No data available
Solubility
8 g/L (20°C)
Cloud Point
---
Appearance
Colorless
Dynamic Viscosity
0.56 mPa s at 20 °C
Softening Point
No data available
Colour Intensity
---
Relative Evaporation Rate
---
Explosive Limits
---
Boiling Point
61 °C / 141.8 °F
Flammability
No data available
Auto Ignition Temperature
No data available
Colour
Colorless
Properties Status
---
Physical State Data
liquid
Molecular Weight
119.38
State Under Standard Conditions
---
Vapor Pressure
213 mbar @ 20 °C
Metal Corrosion
---
Density
1.480
Vapor Density
No data available
Solubility In Fat
---
Relative Density
1.480
Form
---
Odor
aromatic sweet
Crystallisation Point
---
Solidification Point
---
Partition Coefficient
Chloroform: 2, 1-Pentene: 2.66
Voc Content
100
Evaporation Rate
---
Freezing Point
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions. UNSTABLE (REACTIVE) UPON DEPLETION OF INHIBITOR. Light sensitive.

Reactivity

None known, based on information available

Hazardous reactions

Hazardous polymerization does not occur. None under normal processing.

Avoid

Incompatible products. Heat, flames and sparks. Excess heat. Exposure to light. Protect from moisture.

Incompatible

Strong oxidizing agents. Alkali metals. Aluminium. Acetone.

Decomposition

Carbon monoxide (CO). Carbon dioxide (CO₂). Phosgene. Hydrogen chloride gas.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.

Disposal

Waste is classified as hazardous.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN1888
Shipping Name
Chloroform
Transport Class
6.1
Packing Group
III
ADR

No special precautions required.

IMDG

No special precautions required.

IATA

No special precautions required.

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Chloroform known by?

Chloroform is also known as: Methane trichloride; Methenyl trichloride; Formyl trichloride

What is the hazard signal word for Chloroform?

The signal word is danger.

What is the physical form of Chloroform?

Chloroform is a liquid appearing as colorless with colorless color. It has aromatic sweet odor.

What is the solubility of Chloroform?

8 g/L (20°C)

What is Chloroform used for?

Laboratory chemicals. Sector of use: SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites. Product category: PC21 - Laboratory chemicals. Process categories: PROC15 - Use as a laboratory reagent. Environmental release category: ERC6a - Industrial use resulting in manufacture of another substance (use of intermediates)

What are the hazard statements for Chloroform?

This substance has 8 hazard statements:

  • H302: Harmful if swallowed
  • H315: Causes skin irritation
  • H319: Causes serious eye irritation
  • H331: Toxic if inhaled
  • H336: May cause drowsiness or dizziness
  • H351: Suspected of causing cancer
  • H361d: Suspected of damaging the unborn child
  • H372: Causes damage to organs through prolonged or repeated exposure

What is the melting point of Chloroform?

The melting point is -63 °C / -81.4 °F and the boiling point is 61 °C / 141.8 °F.