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Chloroform

DANGER liquid SDS/MSDS

Chemical Product Identification & Regulatory Data

Official chemical identifiers, CAS numbers, and regulatory compliance information

Basic Product Information

Product Name
Chloroform
Product Code
288306
Chemical Name
Chloroform, HPLC Grade
Synonyms
Formyl trichloride

Regulatory Identifiers

CAS Number

Chemical Abstracts Service registry number - unique identifier for chemical substances

EC Number

European Community number - used for regulatory compliance in EU/EEA

Uses Information

Identified Uses
Laboratory chemicals, Synthesis of substances
Uses Advised Against
The product is being supplied under the TSCA R&D Exemption (40 CFR Section 720.36). It is the recipients responsibility to comply with the requirements of the R&D exemption. The product may not be used for a non-exempt commercial purpose under TSCA unless appropriate consent is granted in writing by MilliporeSigma.

Overview

Chloroform (CAS: 67-66-3 ) is a clear substance commonly used laboratory chemicals, synthesis of substances.

Manage Your Safety Data Sheets

Organize and access your chemical safety data with ease.

GHS Hazard Classification & Safety Warnings

Globally Harmonized System (GHS) hazard pictograms, signal words, and safety classifications

Classification Status

Classified

Signal Word

danger (Danger)

Hazard Classifications

Acute Tox. Category 4 H302
Acute Tox. Category 3 H331
Skin Irrit. Category 2 H315
Eye Irrit. Category 2A H319
Carc. Category 2 H351
Repr. Category 2 H361
STOT SE Category 3 H336
STOT RE Category 1 H372
Aquatic Acute Category 3 H402

GHS Hazard Pictograms & Safety Symbols

GHS06 GHS Hazard Pictogram: Acute toxicity hazard - Poisonous materials that can cause death or serious harm

GHS06

GHS07 GHS Hazard Pictogram: Health hazard warning - Materials harmful to health including irritants and sensitizers

GHS07

GHS08 GHS Hazard Pictogram: Serious health hazard - Carcinogenic, mutagenic, or toxic to organs

GHS08

GHS (Globally Harmonized System) pictograms indicate specific chemical hazard categories and safety precautions

Hazard Statements

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H331: Toxic if inhaled.
  • H336: May cause drowsiness or dizziness.
  • H351: Suspected of causing cancer.
  • H361: Suspected of damaging fertility or the unborn child.
  • H372: Causes damage to organs (Liver, Kidney) through prolonged or repeated exposure if swallowed.
  • H402: Harmful to aquatic life.

Precautionary Statements

  • P201: Obtain special instructions before use.
  • P202: Do not handle until all safety precautions have been read and understood.
  • P260: Do not breathe mist or vapors.
  • P264: Wash skin thoroughly after handling.
  • P270: Do not eat, drink or smoke when using this product.
  • P271: Use only outdoors or in a well-ventilated area.
  • P273: Avoid release to the environment.
  • P280: Wear protective gloves/ protective clothing/ eye protection/ face protection.
  • P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
  • P304 + P340 + P311: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor.
  • P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308 + P313: IF exposed or concerned: Get medical advice/ attention.
  • P332 + P313: If skin irritation occurs: Get medical advice/ attention.
  • P337 + P313: If eye irritation persists: Get medical advice/ attention.
  • P362: Take off contaminated clothing and wash before reuse.
  • P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
  • P405: Store locked up.
  • P501: Dispose of contents/ container to an approved waste disposal plant.
  • IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.

Chemical Manufacturers & Supply Chain

Authorized suppliers, manufacturers, and distribution network information

Sigma-Aldrich Inc.

global supplier

๐Ÿ“

3050 SPRUCE ST ST. LOUIS MO 63103 UNITED STATES

๐ŸŒ

US

๐Ÿ“ž

+1 314 771-5765

๐Ÿ“ 

+1 800 325-5052

24/7 Emergency Response & Poison Control

Critical emergency contact numbers for chemical spills, exposure incidents, and medical emergencies

CHEMTREC

๐Ÿ“ž

800-424-9300

๐ŸŒ

US

๐Ÿ•’

24 Hours/day; 7 Days/week

CHEMTREC

๐Ÿ“ž

+1-703-527-3887

๐Ÿ•’

24 Hours/day; 7 Days/week

Chemical Composition & Hazardous Ingredients

Detailed component analysis, concentration ranges, and hazardous substance identification

Product Type

Substance

Chemical Components & Hazardous Substances

Chemical Name CAS Number Concentration Hazardous
Chloroform, HPLC Grade
EC: 200-663-8
67-66-3 100% โš ๏ธ Hazardous
ethanol N/A 1-5% โš ๏ธ Hazardous

Emergency First Aid Measures

Critical first aid procedures for chemical exposure incidents and medical emergencies

๐Ÿซ Inhalation Exposure

After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

๐Ÿ–๏ธ Skin Contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

๐Ÿ‘๏ธ Eye Contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

๐Ÿฝ๏ธ Ingestion/Swallowing

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

๐Ÿšจ Immediate Medical Attention Required

No data available

Medical Treatment

No data available

Related Chemical Substances & Alternative Products

Similar chemicals with comparable safety profiles and industrial applications

Technical Specifications & Material Properties

Physical state, chemical properties, melting point, boiling point, and material characteristics

๐Ÿ“Š Freezing Point
-64 C (-83 F)
๐Ÿ“Š Relative Evaporation Rate
Not available
๐Ÿ‘๏ธ Appearance
clear
๐Ÿ’จ Evaporation Rate
No data available
๐Ÿ“Š Upper Explosive Limit
No data available
๐ŸงŠ Melting Point
-64 C (-83 F)
Critical Property
๐Ÿ“Š Solubility In Fat
Not available
๐Ÿ“Š Softening Point
Not available
๐Ÿ“Š Auto Ignition Temperature
No data available
๐Ÿ“Š State Under Standard Conditions
Not available
๐Ÿ“Š Crystallisation Point
Not available
๐Ÿ“Š Vapor Density
4.12 - (Air = 1.0)
๐Ÿ“Š Molecular Weight
Not available
๐Ÿ“Š Odor Threshold
205 ppm
๐Ÿ“Š Colour Intensity
Not available
๐Ÿ“Š Properties Status
Not available
๐Ÿ“Š Partition Coefficient
No data available
โš–๏ธ Density
1.49 g/cm3 at 25 C (77 F)
Critical Property
๐Ÿ“Š Kinematic Viscosity
No data available
๐Ÿ“Š Voc Content
Not available
๐Ÿ’จ Boiling Point
60.5 - 61.5 C 140.9 - 142.7 F at 1,013.25 hPa
Critical Property
๐Ÿ“Š Explosive Limits
Not available
๐Ÿ“Š Lower Explosive Limit
No data available
๐Ÿงช Ph
No data available
๐Ÿ“Š Bulk Density
Not available
๐Ÿ”ฅ Flash Point
does not flash
Critical Property
๐Ÿงช Physical State
liquid
Critical Property
๐Ÿ“Š Metal Corrosion
Not available
๐Ÿ’ง Solubility
organic solvent at 20 C (68 F) - miscible
๐Ÿ“Š Dynamic Viscosity
No data available
๐ŸŽจ Colour
colorless
๐Ÿ“Š Form
liquid
๐Ÿ’จ Vapor Pressure
210 hPa at 20 C (68 F)
๐Ÿ“Š Solidification Point
Not available
๐Ÿ“Š Solubility In Water
8.7 g/l at 23 C (73 F) - OECD Test Guideline 105 - soluble
๐Ÿ‘ƒ Odor
sweet
๐Ÿ“Š Decomposition Temperature
Distillable in an undecomposed state at normal pressure.
๐Ÿ”ฅ Flammability
No data available
๐Ÿ“Š Relative Density
No data available
๐Ÿ“Š Cloud Point
Not available
๐Ÿ“Š Physical State Data
liquid

Exposure Controls & Personal Protective Equipment (PPE)

Occupational exposure limits, engineering controls, and required safety equipment

๐Ÿงค Hand Protection

Full contact Material: Viton Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Vitoject (KCL 890 / Aldrich Z677698, Size M). Splash contact Material: butyl-rubber Minimum layer thickness: 0.7 mm Break through time: 10 min Material tested:Butoject (KCL 898)

๐Ÿ‘๏ธ Eye Protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

๐Ÿ˜ท Respiratory Protection

Recommended Filter type: Filter type AX The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

๐Ÿฆบ Skin/Body Protection

protective clothing

๐ŸŒ Environmental Exposure Controls

Do not let product enter drains.

Transportation & Shipping Information

UN numbers, shipping names, transport classes, and regulatory transport requirements

๐Ÿท๏ธ UN Number

1888

๐Ÿ“ฆ Proper Shipping Name

ChloroformSOLUTION

โš ๏ธ Transport Hazard Class

6.1

๐Ÿ“‹ Packing Group

III

Chemical Safety FAQ & Common Questions

Most frequently asked questions about safety, handling, storage, and regulatory compliance

What other names is Chloroform known by?

Chloroform is also known as: Formyl trichloride

What is the hazard signal word for Chloroform?

The signal word for this substance is "danger".

What is the physical form of Chloroform?

Chloroform is a liquid appearing as clear with colorless color. It has sweet odor.

What is the solubility of Chloroform?

organic solvent at 20 C (68 F) - miscible

What is Chloroform used for?

Laboratory chemicals, Synthesis of substances

What are the hazard statements for Chloroform?

This substance has 9 hazard statements: H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H331: Toxic if inhaled. H336: May cause drowsiness or dizziness. H351: Suspected of causing cancer. H361: Suspected of damaging fertility or the unborn child. H372: Causes damage to organs (Liver, Kidney) through prolonged or repeated exposure if swallowed. H402: Harmful to aquatic life.

What is the melting point of Chloroform?

The melting point is -64 C (-83 F) and the boiling point is 60.5 - 61.5 C 140.9 - 142.7 F at 1,013.25 hPa.