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Safety Data Sheet EN

Voriconazole N-Oxide

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Voriconazole N-Oxide
Product Code
V760010
Chemical Name
Voriconazole N-Oxide

Regulatory Identifiers

CAS Number
N/A

Identified Uses

To be used only for scientific research and development.

Uses advised against

Not for use in humans or animals.

Manufacturers & Suppliers

T

Toronto Research Chemicals

manufacturer

2 Brisbane Road, Toronto, ON M3J 2J8, CANADA

+14166659696

Emergency Contacts

Toronto Research Chemicals

+14166659696

0800-1700 (GMT-5)

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Toxicity, Oral Cat. 3
Carcinogenicity Cat. 2
Reproductive Toxicity Cat. 2
STOT RE Cat. 2
Aquatic Acute Cat. 3
Aquatic Chronic Cat. 3

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H301 Toxic if swallowed.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility or the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.
H402 Harmful to aquatic life.
H412 Harmful to aquatic life with long lasting effects.

Precautionary Statements

P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P281 Use personal protective equipment as required.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
(oR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol 618109-05-0 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If inhaled, move person to fresh air. If not breathing, give artificial respiration and consult a physician.

Skin contact

Wash affected area with soap and water. Consult a physician if any exposure symptoms are observed.

Eye contact

Immediately rinse eyes with plenty of water for at least 15 minutes. Consult a physician.

Ingestion

Never give anything by mouth to an unconscious person. Rinse mouth with water. Do NOT induce vomiting unless advised to do so by a physician or Poison Control Center. Seek medical attention.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Specific hazards

Carbon oxides, Nitrogen oxides, Hydrogen fluoride

Instructions

Wear self contained breathing apparatus for fire fighting if necessary.

Firefighter Protection

Wear self contained breathing apparatus for fire fighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Environmental

Prevent further leakage or spillage if safe to do so.

Cleanup methods

Pick up and arrange disposal without creating dust. Sweep up and shovel.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Storage

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Storage conditions: -20°C Freezer, Under Inert Atmosphere

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

A laboratory fumehood or other appropriate form of local exhaust ventilation should be used to avoid exposure.

Hands

Gloves should be used when handling this material. Gloves are to be inspected prior to use. Contaminated gloves are to be removed using proper glove removal technique so that the outer surface of the glove does not contact bare skin. Dispose of contaminated gloves after use in compliance with good laboratory practices and local requirements. Gloves used for incidental exposures (splash protection) should be designated as "chemical resistant" by EU standard EN 374 with the resistance codes corresponding to the anticipated use of the material. Unrated gloves are not recommended. Suggested gloves: AnsellPro Sol-Vax nitrile gloves style 37-175, 15 mil thickness. Penetration time has not been determined. Gloves used for prolonged direct exposure (immersion) should be designated "chemical resistant" as per EN 734 with the resistance codes corresponding to the anticipated use of the material. Suggested gloves: AnsellPro Viton/Bulyl gloves style 38-612, 4/8 mil thickness. Penetration time has not been determined. These recommendations may not apply if the material is mixed with any other chemical, or dissolved into a solution. A risk assessment must be performed to ensure the gloves will still offer acceptable protection.

Eyes

Safety goggles or face shield. All equipment should have been tested and approved under appropriate standards, such as NIOSH (US), CSA (Canada), or EN 166 (EU).

Respiratory

Recommended respirators are NIOSH-approved N100 or CEN-approved FFP3 particulate respirators. These are to be only used as a backup to local exhaust ventilation or other engineering controls. If the respirator is the only means of protection, a full-face supplied air respirator must be used.

Skin/Body

Fire resistant (Nomex) coveralls or chemical-resistant bodysuit (laminated Tychem SL or equivalent).

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Solubility In Fat
---
Auto Ignition Temperature
No data available
Freezing Point
>70 (dec.)
Odor
No data available
Molecular Weight
---
Ph
No data available
Flammability
No data available
Form
---
Metal Corrosion
---
Kinematic Viscosity
---
Crystallisation Point
---
Softening Point
---
Boiling Point
No data available
Evaporation Rate
No data available
Colour
---
Cloud Point
---
Melting Point
>70°C (dec.)
Properties Status
---
Dynamic Viscosity
---
Flash Point
No data available
Physical State Data
solid
Explosive Limits
---
Relative Evaporation Rate
---
Vapor Pressure
No data available
Density
---
Bulk Density
---
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Relative Density
No data available
Voc Content
---
Partition Coefficient
No data available
State Under Standard Conditions
---
Vapor Density
No data available
Decomposition Temperature
No data available
Solubility
Chloroform, Dichloromethane, Ethyl Acetate
Colour Intensity
---
Physical State
Solid
Solidification Point
---
Solubility In Water
---
Odor Threshold
No data available
Appearance
Off-White Solid
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable at recommended storage conditions.

Reactivity

No data available

Hazardous reactions

No data available

Avoid

No data available

Incompatible

Strong oxidizing materials.

Decomposition

No data available

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Product may be burned in an incinerator equipped with afterburner and scrubber. Excess and expired materials are to be offered to a licensed hazardous material disposal company.

Disposal

Excess and expired materials are to be offered to a licensed hazardous material disposal company.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
Toxic solids, organic, n.o.s. (Voriconazole N-Oxide)
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

This safety data sheet complies with the requirements of WHMIS (Canada), OSHA 1910.1200 (US), and EU Regulation EC No. 1907/2006 (European Union).

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Voriconazole N-Oxide?

The signal word is danger.

What is the physical form of Voriconazole N-Oxide?

Voriconazole N-Oxide is a solid appearing as off-white solid . It has no data available odor.

What is the solubility of Voriconazole N-Oxide?

Chloroform, Dichloromethane, Ethyl Acetate

What is Voriconazole N-Oxide used for?

To be used only for scientific research and development.

What are the hazard statements for Voriconazole N-Oxide?

This substance has 6 hazard statements:

  • H301: Toxic if swallowed.
  • H351: Suspected of causing cancer.
  • H361: Suspected of damaging fertility or the unborn child.
  • H373: May cause damage to organs through prolonged or repeated exposure.
  • H402: Harmful to aquatic life.
  • H412: Harmful to aquatic life with long lasting effects.

What is the melting point of Voriconazole N-Oxide?

The melting point is >70°C (dec.) and the boiling point is No data available.