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Safety Data Sheet EN

Voriconazole N-Oxide

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Voriconazole N-Oxide
Product Code
V760010

Regulatory Identifiers

CAS Number
N/A

Identified Uses

To be used only for scientific research and development.

Uses advised against

Not for use in humans or animals.

Manufacturers & Suppliers

T

Toronto Research Chemicals

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2 Brisbane Road Toronto, ON M3J 2J8 CANADA

Emergency Contacts

Emergency Contact

+14166659696

0800-1700 (GMT-5)

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox.
Repr.
Carc.

GHS Pictograms

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H301 Toxic if swallowed.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility or the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.
H402 Harmful to aquatic life.
H412 Harmful to aquatic life with long lasting effects.

Precautionary Statements

P201 Obtain special instructions before use.
P201 Use personal protective equipment as required.
P260
P281 Do not breathe dust/fume/gas/mist/vapours/spray.
P281 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type Substance
Chemical Name CAS Number Concentration Hazardous
(aR,BS)-a-(2,4-Difluorophenyl)-5-fluoro--methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol 618109-05-0 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

If inhaled, move person to fresh air. If not breathing, give artificial respiration and consult a physician.

Skin contact

Wash affected area with soap and water. Consult a physician if any exposure symptoms are observed.

Symptoms: exposure symptoms are observed.

Eye contact

Immediately rinse eyes with plenty of water for at least 15 minutes. Consult a physician.

Ingestion

Never give anything by mouth to an unconscious person. Rinse mouth with water. Do NOT induce vomiting unless advised to do so by a physician or Poison Control Center. Seek medical attention.

Immediate Medical Attention

No data available

Related Substances

Similar chemicals with comparable safety profiles

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

A laboratory fumehood or other appropriate form of local exhaust ventilation should be used to avoid exposure.

Hands

Gloves should be used when handling this material. Gloves are to be inspected prior to use. Contaminated gloves are to be removed using proper glove removal technique so that the outer surface of the glove does not contact bare skin. Dispose of contaminated gloves after use in compliance with good laboratory practices and local requirements. Gloves used for incidental exposures (splash protection) should be designated as "chemical resistant" by EU standard EN 374 with the resistance codes corresponding to the anticipated use of the material. Unrated gloves are not recommended. Suggested gloves: AnsellPro Sol-Vex nitrile gloves style 37-175, 15 mil thickness. Penetration time has not been determined. Gloves used for prolonged direct exposure (immersion) should be designated "chemical resistant" as per EN 734 with the resistance codes corresponding to the anticipated use of the material. Suggested gloves: AnsellPro Viton/Butyl gloves style 38-612, 4/8 mil thickness. Penetration time has not been determined. These recommendations may not apply if the material is mixed with any other chemical, or dissolved into a solution. A risk assessment must be performed to ensure the gloves will still offer acceptable protection.

Eyes

Safety goggles or face shield. All equipment should have been tested and approved under appropriate standards, such as NIOSH (US), CSA (Canada), or EN 166 (EU).

Respiratory

Recommended respirators are NIOSH-approved N100 or CEN-approved FFP3 particulate respirators. These are to be only used as a backup to local exhaust ventilation or other engineering controls. If the respirator is the only means of protection, a full-face supplied air respirator must be used.

Skin/Body

Fire resistant (Nomex) coveralls or chemical-resistant bodysuit (laminated Tychem SL or equivalent).

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
---
Physical State Data
---
State Under Standard Conditions
---
Appearance
Off-White Solid
Colour
---
Colour Intensity
---
Form
---
Odor
No data available
Odor Threshold
No data available
Ph
No data available
Melting Point
>70 (dec.)
Boiling Point
No data available
Flash Point
No data available
Freezing Point
>70 (dec.)
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
No data available
Vapor Pressure
No data available
Vapor Density
No data available
Relative Density
No data available
Bulk Density
---
Density
---
Flammability
No data available
Upper Explosive Limit
No data available
Lower Explosive Limit
No data available
Explosive Limits
---
Auto Ignition Temperature
No data available
Decomposition Temperature
No data available
Solubility
Chloroform, Dichloromethane, Ethyl Acetate
Partition Coefficient
No data available
Solubility In Water
---
Solubility In Fat
---
Molecular Weight
---
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
---
Kinematic Viscosity
---
Properties Status
---
14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2811
Shipping Name
TOXIC SOLID, ORGANIC, N.O.S. (Voriconazole N-Oxide)
Transport Class
6.1
Packing Group
III
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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for Voriconazole N-Oxide?

The signal word is danger.

What is the solubility of Voriconazole N-Oxide?

Chloroform, Dichloromethane, Ethyl Acetate

What is Voriconazole N-Oxide used for?

To be used only for scientific research and development.

What are the hazard statements for Voriconazole N-Oxide?

This substance has 6 hazard statements:

  • H301: Toxic if swallowed.
  • H351: Suspected of causing cancer.
  • H361: Suspected of damaging fertility or the unborn child.
  • H373: May cause damage to organs through prolonged or repeated exposure.
  • H402: Harmful to aquatic life.
  • H412: Harmful to aquatic life with long lasting effects.

What is the melting point of Voriconazole N-Oxide?

The melting point is >70 (dec.) and the boiling point is No data available.

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