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Safety Data Sheet EN

Metronidazole

CAS 443-48-1
EC 207-136-1

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Metronidazole
Synonyms
Metronidazolum, Metronidazol, Métronidazole, Metronidazol

Regulatory Identifiers

CAS Number
443-48-1 Check regulations →
EC Number
207-136-1 Check regulations →

Identified Uses

Active Pharmaceutical Ingredient or Excipient.

Manufacturers & Suppliers

FAC SECUNDUM ARTEM NV logo

FAC SECUNDUM ARTEM NV

manufacturer

Oostmalsebaan 1c (unit 5), 2960 Sint-Lenaarts, Belgium

(+32) (0)3 457 11 76

http://www.magis-pharma.be

Emergency Contacts

Belgisch Antigifcentrum / Centre Antipoisons Belge

(+32) (0)70 245 245

Service 24/7

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Acute Tox. Cat. 4 H302
Skin Irrit. Cat. 2 H315
Eye Irrit. Cat. 2 H319
Muta. Cat. 2 H341
STOT SE Cat. 3 H335
Carc. Cat. 1B H350

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H341 Suspected of causing genetic defects.
H350 May cause cancer.

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P281 Use personal protective equipment as required.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor/... if you feel unwell.
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P501 Dispose of contents/container in accordance with local/regional/national/international regulation.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance

Metronidazole substance

Chemical Name CAS Number Concentration Hazardous
Metronidazole EC: 207-136-1 443-48-1 99 - 101% No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Take to fresh air. If breathing is irregular, call a doctor immediately. Only give artificial respiration if breathing stops or under medical supervision.

Skin contact

Wash immediately with plenty of soap and water for at least 15 minutes. Remove all contaminated clothing immediately. Get medical attention if irritation develops and persists.

Eye contact

Remove contact lenses and rinse immediately with plenty of water, including under the eyelids, for at least 15 minutes. Get medical attention.

Ingestion

If conscious, give the victim plenty of water to drink. Never give anything by mouth to an unconscious person. Call a doctor immediately.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Foam, dry powder, carbon dioxide, sand, water mist. Containers exposed to fire: Water spray or fog.

Unsuitable media

Direct water jet.

Specific hazards

In case of fire, fumes harmful to health may be produced.

Instructions

Cool containers with water to prevent decomposition of product and development of potential health hazards. Always use full fire protection.

Firefighter Protection

Helmet with visor, flame retardant clothing (jacket and trousers with straps around the arms, legs and waist, EN 469), gloves (fireproof and dielectric, EN 659), a face mask with full face shield covering the operator or the car (self protective) in case of large amounts of smoke, a self-contained breathing apparatus (EN 137).

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Equip clean-up personnel with appropriate protective equipment. Ventilate area and evacuate unnecessary personnel.

Environmental

Avoid penetration of the product into sewers, surface and groundwater.

Cleanup methods

Collect dry, place in a bag and keep for later disposal as waste. Wash the place where the product has been spilled, once it has been completely removed.

Materials: bag

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handle the product after consulting all other sections of this safety data sheet.

Storage

Keep container closed, in a dry, well-ventilated place.

Hygiene

Do not eat, drink or smoke during use. Remove contaminated clothing and protective equipment before entering eating areas.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure good ventilation at the workplace by effective local suction.

Hands

Handle with gloves. The selected protective gloves must comply with the specifications of EU Directive 89/686/EEC and the derived EN 374 standard.

Eyes

Protective face shields and safety goggles according to EN166.

Respiratory

Where risk assessment shows that air-purifying respirators are appropriate, use dust mask type N95 (USA) or type P1 (EN 143). Use respirators and components tested and approved under appropriate governmental standards such as NIOSH (US) or CEN (EU).

Skin/Body

Choose body protection according to the quantity and concentration of the hazardous substance in the workplace.

Environmental

Not available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Properties Status
---
Flammability
Not available.
Vapor Pressure
Not available.
Colour
White or yellowish
Vapor Density
Not available.
Freezing Point
159 °C to 163 °C
Metal Corrosion
---
Bulk Density
---
Boiling Point
Not available.
State Under Standard Conditions
---
Solubility In Water
Slightly soluble in water.
Colour Intensity
---
Voc Content
---
Molecular Weight
---
Physical State Data
solid
Lower Explosive Limit
Not available.
Auto Ignition Temperature
Not available.
Form
crystalline powder
Decomposition Temperature
Not available.
Physical State
crystalline powder
Relative Density
Not available.
Crystallisation Point
---
Dynamic Viscosity
---
Ph
Not available.
Softening Point
---
Melting Point
159 °C to 163 °C
Solubility In Fat
---
Evaporation Rate
Not available.
Odor Threshold
Not available.
Appearance
White or yellowish, crystalline powder.
Cloud Point
---
Density
0.652 g/ml
Solubility
Slightly soluble in acetone, in alcohol and in methylene chloride.
Kinematic Viscosity
---
Flash Point
Not available.
Partition Coefficient
LowPow -0.02
Solidification Point
---
Odor
Odourless.
Explosive Limits
---
Relative Evaporation Rate
---
Upper Explosive Limit
Not available.
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended handling and storage conditions (see section 7).

Reactivity

No special conditions.

Hazardous reactions

Decomposition by heat may produce toxic fumes of CO, CO₂ and NOₓ. The product has no possibility of hazardous polymerisation.

Avoid

Avoid any type of incorrect handling: high pressures and/or temperatures. Direct sunlight.

Incompatible

Strong oxidising agents.

Decomposition

Toxic fumes of carbon oxides (COₓ) and nitrogen oxides (NOₓ).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Treatment

Dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.

Disposal

Consider all federal, state and local environmental regulations. Contact a licensed professional waste disposal service for disposal of this material.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

Shipping Name
Not classified.
Transport Class
Not classified.
Packing Group
Not classified.
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

Hazard symbols: Harmful, Irritant. Risk phrases: R22 Harmful if swallowed, R36/37/38 Irritating to eyes, respiratory system and skin, R45 May cause cancer. Safety phrases: S23, S26, S36/37/39.

Chemical Safety Assessment Not performed
?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Metronidazole known by?

Metronidazole is also known as: Metronidazolum, Metronidazol, Métronidazole, Metronidazol

What is the hazard signal word for Metronidazole?

The signal word is danger.

What is the physical form of Metronidazole?

Metronidazole is a crystalline powder appearing as white or yellowish, crystalline powder. with white or yellowish color. It has odourless. odor.

What is the solubility of Metronidazole?

Slightly soluble in acetone, in alcohol and in methylene chloride.

What is Metronidazole used for?

Active Pharmaceutical Ingredient or Excipient.

What are the hazard statements for Metronidazole?

This substance has 6 hazard statements:

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.
  • H341: Suspected of causing genetic defects.
  • H350: May cause cancer.

What is the melting point of Metronidazole?

The melting point is 159 °C to 163 °C and the boiling point is Not available..