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Safety Data Sheet EN

Mannitol

CAS 87-78-5
EC 201-770-2

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Mannitol
Synonyms
mannitol,DL-Mannitol

Regulatory Identifiers

CAS Number
87-78-5 Check regulations →
EC Number
201-770-2 Check regulations →

Identified Uses

For R&D use only. Not for medicinal, household or other use.

Manufacturers & Suppliers

C

Chemicalbook

manufacturer

Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing

400-158-6606

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified no signal word

GHS Pictograms

Hazard Statements

Precautionary Statements

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Mannitol EC: 201-770-2 87-78-5 --- No
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Symptoms: Coughing may result from inhalation.

Skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Symptoms: It may cause irritation of the skin. Skin contact may cause discoloration of sensitive skin.

Eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Symptoms: Eye contact may cause redness and pain.

Ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Symptoms: Ingestion may cause gastric irritation.

Immediate Medical Attention

Consult a doctor immediately (inhalation), Consult a doctor (skin/eye), Call a doctor or Poison Control Center immediately (ingestion).

Medical Treatment

Six patients with severe mannitol intoxication were treated with hemodialysis & one with peritoneal dialysis. Ideal treatment is hemodialysis which rapidly removes mannitol (half-life, 6 hr) & replaces it with sodium; peritoneal dialysis removed mannitol slowly (half-life, 21 hr).

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.

Specific hazards

This chemical is probably combustible.

Firefighter Protection

Wear self-contained breathing apparatus for firefighting if necessary.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak.

Environmental

Prevent further spillage or leakage if it is safe to do so. Discharge into the environment must be avoided.

Cleanup methods

Collect and arrange disposal.

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Storage

Mannitol solutions should be stored at room temperature and protected from freezing.

Hygiene

Wear suitable protective clothing. Avoid contact with skin and eyes.

Fire prevention

Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Ensure adequate ventilation.

Hands

Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Eyes

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Respiratory

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Skin/Body

Wear fire/flame resistant and impervious clothing.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Vapor Pressure
no data available
Upper Explosive Limit
no data available
Dynamic Viscosity
---
Molecular Weight
---
Lower Explosive Limit
no data available
Voc Content
---
Odor Threshold
---
Softening Point
---
State Under Standard Conditions
---
Evaporation Rate
---
Colour Intensity
---
Metal Corrosion
---
Form
crystalline powder or free-flowing granules
Solubility In Water
---
Solidification Point
---
Melting Point
166-168°C
Crystallisation Point
---
Cloud Point
---
Relative Evaporation Rate
---
Ph
no data available
Boiling Point
494.9°C at 760 mmHg
Auto Ignition Temperature
no data available
Relative Density
---
Properties Status
---
Freezing Point
---
Appearance
Odorless white crystalline powder or free-flowing granules
Solubility In Fat
---
Flammability
no data available
Kinematic Viscosity
no data available
Colour
Orthorhombic needles from alc
Partition Coefficient
no data available
Physical State Data
solid
Flash Point
292.5°C
Density
1.596 g/cm3
Bulk Density
---
Vapor Density
---
Odor
Odorless
Decomposition Temperature
no data available
Explosive Limits
---
Solubility
greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
Physical State
white crystalline powder or free-flowing granules
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Mannitol 25% (Invenex) was chemically and physically stable after five autoclavings at 250 deg F for 15 min.

Reactivity

no data available

Hazardous reactions

A sugar alcohol. More closely related to carbohydrates than to other polyhydric alcohols [Noller]. Flammable and/or toxic gases are generated by the combination with alkali metals, nitrides, strong reducing agents and strong oxidizing agents.

Avoid

no data available

Incompatible

It has been stated that mannitol is incompatible in strongly acidic and alkaline solutions.

Decomposition

When heated to decomposition it emits acrid smoke and fumes.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

Disposal

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Mannitol known by?

Mannitol is also known as: mannitol,DL-Mannitol

What is the hazard signal word for Mannitol?

The signal word is no signal word.

What is the physical form of Mannitol?

Mannitol is a white crystalline powder or free-flowing granules appearing as odorless white crystalline powder or free-flowing granules with orthorhombic needles from alc color. It has odorless odor.

What is the solubility of Mannitol?

greater than or equal to 100 mg/mL at 68° F (NTP, 1992)

What is Mannitol used for?

For R&D use only. Not for medicinal, household or other use.

What are the hazard statements for Mannitol?

This substance has 1 hazard statement:

What is the melting point of Mannitol?

The melting point is 166-168°C and the boiling point is 494.9°C at 760 mmHg.