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Safety Data Sheet EN

(±)-Epichlorohydrin

CAS 106-89-8

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
(±)-Epichlorohydrin
Product Code
02578
Chemical Name
(±)-Epichlorohydrin

Regulatory Identifiers

CAS Number
106-89-8 Check regulations →
REACH No.
01-2119457436-33-XXXX

Identified Uses

Laboratory chemicals, Manufacture of substances

Manufacturers & Suppliers

M

Merck Life Science BV/SRL

manufacturer

Brusselsesteenweg 288, B-3090 OVERIJSE

+32 (0)3 899-1301

Emergency Contacts

CHEMTREC

+(32) 28 083237

Anti-poison centre

070 245245

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 3 H226
Acute Tox. Cat. 3 H301
Acute Tox. Cat. 3 H331
Acute Tox. Cat. 3 H311
Skin Corr. Cat. 1B H314
Eye Dam. Cat. 1 H318
Skin Sens. Cat. 1 H317
Carc. Cat. 1B H350
Repr. Cat. 2 H361f

GHS Pictograms

GHS02 - Flammable

GHS02

GHS05 - Corrosive

GHS05

GHS06 - Acute toxicity

GHS06

GHS08 - Serious health hazard

GHS08

Hazard Statements

H226 Flammable liquid and vapor.
H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H350 May cause cancer.
H361f Suspected of damaging fertility.

Precautionary Statements

P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
1-chloro-2,3-epoxypropane EC: 203-439-8 106-89-8 --- Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Move to fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

Skin contact

Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye contact

Rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

Ingestion

Give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible. Do not attempt to neutralise.

Immediate Medical Attention

Immediately call in physician for inhalation, skin contact, and ingestion. Immediately call in ophthalmologist for eye contact.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards

Carbon oxides, Hydrogen chloride gas, Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air at elevated temperatures. Development of hazardous combustion gases or vapours possible in the event of fire.

Instructions

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet.

Firefighter Protection

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental

Do not let product enter drains. Risk of explosion.

Cleanup methods

Take up carefully with liquid-absorbent material (e.g. Chemizorb®).

Materials: liquid-absorbent material (e.g. Chemizorb®)

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

Storage

Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons. Store under inert gas.

Hygiene

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Hands

Full contact: Material: butyl-rubber, Minimum layer thickness: 0,7 mm, Break through time: 480 min, Material tested: Butoject® (KCL 898). Splash contact: Material: Viton®, Minimum layer thickness: 0,7 mm, Break through time: 60 min, Material tested: Vitoject® (KCL 890 / Aldrich Z677698, Size M). When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eyes

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Respiratory

Recommended Filter type: Filter A-(P3). The entrepreneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Skin/Body

Flame retardant antistatic protective clothing.

Environmental

Do not let product enter drains. Risk of explosion.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Melting Point
-57 °C
Kinematic Viscosity
No data available
Colour Intensity
---
Form
---
Cloud Point
---
Flammability
No data available
Odor
stinging
Properties Status
---
Relative Evaporation Rate
---
Physical State
clear, liquid
Odor Threshold
---
Partition Coefficient
log Pow: 0,45 at 25 °C - Bioaccumulation is not expected. n-octanol/water
Colour
colorless
Vapor Pressure
16,5 hPa at 20 °C; 22,8 hPa at 25 °C
Appearance
clear, liquid
Solidification Point
---
Softening Point
---
Relative Density
1,18 at 20 °C
State Under Standard Conditions
---
Upper Explosive Limit
21 % (V)
Solubility In Fat
---
Vapor Density
---
Explosive Limits
---
Physical State Data
liquid
Flash Point
28 °C - DIN 51755 Part 1
Ph
No data available
Auto Ignition Temperature
385 °C at 1.013 hPa
Evaporation Rate
---
Molecular Weight
---
Solubility
---
Boiling Point
115 - 117 °C
Metal Corrosion
---
Lower Explosive Limit
3,8 % (V)
Decomposition Temperature
225 °C
Voc Content
---
Density
1,183 g/mL at 25 °C
Freezing Point
---
Crystallisation Point
---
Bulk Density
---
Solubility In Water
ca.65,9 g/l at 25 °C - completely soluble
Dynamic Viscosity
ca.1,03 mPa.s at 20 °C
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

The product is chemically stable under standard ambient conditions (room temperature).

Reactivity

Vapor/air-mixtures are explosive at intense warming.

Hazardous reactions

Risk of explosion with: aluminium chloride, Amines, anilines, metallic chlorides, Chlorites, Tin, Zinc. Exothermic reaction with: Alkali metals, Alcohols, alkalines, Water, Zinc, Tin, acids, Ethyleneimine, aromatic amines, Nitric acid, sulfuric acid, trichloroethene

Avoid

Heat, flames and sparks. Heating.

Incompatible

No data available

Decomposition

In the event of fire: see section 5

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
2023
Shipping Name
EPICHLOROHYDRIN
Transport Class
6.1 (3)
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for (±)-Epichlorohydrin?

The signal word is danger.

What is the physical form of (±)-Epichlorohydrin?

(±)-Epichlorohydrin is a clear, liquid appearing as clear, liquid with colorless color. It has stinging odor.

What is (±)-Epichlorohydrin used for?

Laboratory chemicals, Manufacture of substances

What are the hazard statements for (±)-Epichlorohydrin?

This substance has 6 hazard statements:

  • H226: Flammable liquid and vapor.
  • H301 + H311 + H331: Toxic if swallowed, in contact with skin or if inhaled.
  • H314: Causes severe skin burns and eye damage.
  • H317: May cause an allergic skin reaction.
  • H350: May cause cancer.
  • H361f: Suspected of damaging fertility.

What is the melting point of (±)-Epichlorohydrin?

The melting point is -57 °C and the boiling point is 115 - 117 °C.