NextSDS Logo
Safety Data Sheet EN

1,1,3,3-Tetramethylguanidine

CAS 80-70-6
EC 201-302-7

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report.

Get Free Audit
01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
1,1,3,3-Tetramethylguanidine
Product Code
221290000; 221290020; 221290025; 221290050; 221291000; 221295000
Chemical Name
1,1,3,3-Tetramethylguanidine

Regulatory Identifiers

CAS Number
80-70-6 Check regulations →
EC Number
201-302-7 Check regulations →

Identified Uses

Laboratory chemicals.

Uses advised against

No Information available

Manufacturers & Suppliers

F

Fisher Scientific UK

national supplier

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

T

Thermo Fisher Scientific

national supplier

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

Emergency Contacts

Emergency Contact

001-201-796-7100

Emergency Contact

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 3 H226
Acute Tox. Cat. 4 H302
Acute Tox. Cat. 4 H332
Skin Corr. Cat. 1B H314
Eye Dam. Cat. 1 H318

GHS Pictograms

GHS02 - Flammable

GHS02

GHS05 - Corrosive

GHS05

GHS07 - Health hazard

GHS07

Hazard Statements

H226 Flammable liquid and vapor
H302 + H332 Harmful if swallowed or if inhaled
H314 Causes severe skin burns and eye damage

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 Immediately call a POISON CENTER or doctor/physician

Get a free compliance audit

Upload your SDS inventory and get a detailed compliance report

Free Audit
03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type substance
Chemical Name CAS Number Concentration Hazardous
Guanidine, N,N,N',N'-tetramethyl- EC: 201-302-7 80-70-6 99% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If not breathing, give artificial respiration.

Symptoms: Difficulty in breathing.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Ingestion

Do NOT induce vomiting. Call a physician or poison control center immediately.

Symptoms: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation

Immediate Medical Attention

Immediate medical attention is required.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Carbon dioxide (CO2). Dry chemical. Chemical foam. Water mist may be used to cool closed containers.

Unsuitable media

No information available.

Specific hazards

Flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Environmental

See Section 12 for additional Ecological Information.

Cleanup methods

Soak up with inert absorbent material, keep in suitable, closed containers for disposal

Materials: sand, silica gel, acid binder, universal binder, sawdust

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Do not breathe mist/vapors/spray. Do not get in eyes, on skin, or on clothing. Do not ingest. If swallowed then seek immediate medical assistance. Handle product only in closed system or provide appropriate exhaust ventilation. Use spark-proof tools and explosion-proof equipment. Use only non-sparking tools. Wear personal protective equipment/face protection. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges.

Storage

Keep in a dry, cool and well-ventilated place. Keep container tightly closed.

Hygiene

Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Use explosion-proof electrical/ventilating/lighting equipment. Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Nitrile rubber, Neoprene, Natural rubber, PVC. Breakthrough time: See manufacturers recommendations. EU standard: EN 374.

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced Recommended Filter type: Organic gases and vapours filter Type A Brown conforming to EN14387. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask :- Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141 When RPE is used a face piece Fit Test should be conducted

Skin/Body

Wear appropriate protective gloves and clothing to prevent skin exposure. Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Remove gloves with care avoiding skin contamination.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
Liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
Light yellow
Colour
---
Colour Intensity
---
Form
---
Odor
Ammonia-like
Odor Threshold
No data available
Ph
12.7 (10 g/L (25℃))
Melting Point
-30 °C / -22 ºF
Boiling Point
160 - 162 °C / 320 - 323.6 ºF
Flash Point
50 ℃ / 122 ºF (Method - No information available)
Freezing Point
---
Softening Point
---
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
---
Vapor Pressure
0.26 hPa @ 25 ℃
Vapor Density
No information available
Relative Density
---
Bulk Density
Not applicable
Density
0.910
Flammability
Flammable (On basis of test data)
Upper Explosive Limit
7.5
Lower Explosive Limit
1
Explosive Limits
---
Auto Ignition Temperature
350 ℃ / 662 ºF
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
Guanidine, N,N,N',N'-tetramethyl-: -0.49
Solubility In Water
Miscible
Solubility In Fat
---
Molecular Weight
115.18
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
0.002 Pa . s at 20 ℃
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Hygroscopic.

Reactivity

None known, based on information available

Hazardous reactions

Hazardous polymerization does not occur. No information available.

Avoid

Keep away from open flames, hot surfaces and sources of ignition.

Incompatible

Acids. Strong oxidizing agents. Strong acids. Acid anhydrides. Acid chlorides. Carbon dioxide (CO2).

Decomposition

Nitrogen oxides (NOx). Carbon monoxide (CO). Carbon dioxide (CO2).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2920
Shipping Name
Corrosive liquid, flammable, n.o.s.
Transport Class
8
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What is the hazard signal word for 1,1,3,3-Tetramethylguanidine?

The signal word is danger.

What is the physical form of 1,1,3,3-Tetramethylguanidine?

1,1,3,3-Tetramethylguanidine is a liquid appearing as light yellow . It has ammonia-like odor.

What is 1,1,3,3-Tetramethylguanidine used for?

Laboratory chemicals.

What are the hazard statements for 1,1,3,3-Tetramethylguanidine?

This substance has 3 hazard statements:

  • H226: Flammable liquid and vapor
  • H302 + H332: Harmful if swallowed or if inhaled
  • H314: Causes severe skin burns and eye damage

What is the melting point of 1,1,3,3-Tetramethylguanidine?

The melting point is -30 °C / -22 ºF and the boiling point is 160 - 162 °C / 320 - 323.6 ºF.