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Safety Data Sheet EN

Mitomycin C

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Mitomycin C
Product Code
226940000; 226940020
Synonyms
Ametycine

Regulatory Identifiers

CAS Number
N/A

Identified Uses

Laboratory chemicals

Uses advised against

No Information available

Manufacturers & Suppliers

F

Fisher Scientific UK

national supplier

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

T

Thermo Fisher Scientific

national supplier

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

Emergency Contacts

Information US

001-800-227-6701

Information Europe

+32 14 57 52 11

Emergency Number US

001-201-796-7100

Emergency Number Europe

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified warning

Hazard Classifications

Acute Tox. Cat. 4 H302
Carc. Cat. 2 H351

GHS Pictograms

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H302 Harmful if swallowed
H351 Suspected of causing cancer

Precautionary Statements

P201 Obtain special instructions before use
P280 Wear protective gloves/protective clothing/eye protection/face protection
P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P308 + P313 IF exposed or concerned: Get medical advice/attention

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Sodium chloride EC: 231-598-3 7647-14-5 96% No
Mitomycin-C EC: 200-008-6 50-07-7 4% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. If not breathing, give artificial respiration.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Ingestion

Do NOT induce vomiting.

Immediate Medical Attention

Get medical attention. Get medical attention immediately if symptoms occur. Call a physician or poison control center immediately.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.

Unsuitable media

No information available.

Specific hazards

Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Use personal protective equipment as required. Ensure adequate ventilation. Avoid dust formation. Avoid contact with skin, eyes or clothing.

Environmental

Avoid release to the environment. See Section 12 for additional Ecological Information.

Cleanup methods

Sweep up and shovel into suitable containers for disposal.

Materials: suitable containers

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Wear personal protective equipment/face protection. Avoid contact with skin, eyes or clothing. Avoid ingestion and inhalation.

Storage

Keep containers tightly closed in a dry, cool and well-ventilated place.

Hygiene

Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Use only under a chemical fume hood. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. Glove material: Nitrile rubber, Neoprene, Natural rubber, PVC. Breakthrough time: See manufacturers recommendations. EU standard: EN 374. (minimum requirement)

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: Particulates filter conforming to EN 143. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Particle filtering: EN149:2001. When RPE is used a face piece Fit Test should be conducted

Skin/Body

Wear appropriate protective gloves and clothing to prevent skin exposure. Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information). Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Remove gloves with care avoiding skin contamination.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

State Under Standard Conditions
---
Partition Coefficient
---
Freezing Point
---
Physical State Data
solid
Ph
5.5-7.0 (saturated solution)
Solubility In Water
Soluble
Voc Content
---
Physical State
Solid
Kinematic Viscosity
---
Odor
Odorless
Odor Threshold
No data available
Molecular Weight
334.32
Upper Explosive Limit
---
Solidification Point
---
Melting Point
> 360 °C / 680 °F
Auto Ignition Temperature
No data available
Softening Point
No data available
Density
No data available
Vapor Density
Not applicable
Properties Status
---
Explosive Limits
---
Relative Evaporation Rate
---
Form
---
Lower Explosive Limit
---
Vapor Pressure
No data available
Colour Intensity
---
Bulk Density
No data available
Boiling Point
No information available
Evaporation Rate
Not applicable - Solid
Relative Density
---
Decomposition Temperature
No data available
Crystallisation Point
---
Appearance
Blue
Solubility In Fat
---
Flammability
No information available
Cloud Point
---
Colour
---
Dynamic Viscosity
---
Flash Point
No information available
Metal Corrosion
---
Solubility
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under normal conditions.

Reactivity

None known, based on information available

Hazardous reactions

Hazardous polymerization does not occur. None under normal processing.

Avoid

Avoid dust formation. Incompatible products. Excess heat. Exposure to light.

Incompatible

Strong oxidizing agents. Strong acids. Strong bases.

Decomposition

Nitrogen oxides (NOx). Carbon monoxide (CO). Carbon dioxide (CO₂).

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2811
Shipping Name
Toxic solid, organic, n.o.s.
Transport Class
6.1
Packing Group
III
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

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Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Mitomycin C known by?

Mitomycin C is also known as: Ametycine

What is the hazard signal word for Mitomycin C?

The signal word is warning.

What is the physical form of Mitomycin C?

Mitomycin C is a solid appearing as blue . It has odorless odor.

What is Mitomycin C used for?

Laboratory chemicals

What are the hazard statements for Mitomycin C?

This substance has 2 hazard statements:

  • H302: Harmful if swallowed
  • H351: Suspected of causing cancer

What is the melting point of Mitomycin C?

The melting point is > 360 °C / 680 °F and the boiling point is No information available.