Identification
Product identifiers, regulatory numbers, and supplier information
Product Information
- Product Name
- Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments
- Product Code
- 83640
- Chemical Name
- Acetonitrile
- Synonyms
- Cyanomethane, Ethanenitrile, Ethanoic acid nitrile, Methyl cyanide
Regulatory Identifiers
- CAS Number
- 75-05-8 Check regulations →
- REACH No.
- 01-2119471307-38-XXXX
Identified Uses
General chemical reagent
Uses advised against
The product, as such or as a component of a mixture, is not intended to be used by consumers (as defined by the REACH Regulation).
Manufacturers & Suppliers
VWR International B.V.
national supplier
Orlyplein 85, 1043 DS Amsterdam, Nederland
+31 20 480 8410
Emergency Contacts
National Poisons Information Center (NVIC)
030 2748888
Hazard Identification
GHS classification, signal word, pictograms, and hazard statements
Hazard Classifications
GHS Pictograms
GHS02
GHS07
Hazard Statements
Precautionary Statements
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Composition / Information on Ingredients
Chemical components, concentration ranges, and hazardous substance identification
| Chemical Name | CAS Number | Concentration | Hazardous |
|---|---|---|---|
| Acetonitrile EC: 200-835-2 | 75-05-8 | --- | No |
First Aid Measures
Emergency procedures for chemical exposure incidents
Remove casualty to fresh air and keep warm and at rest. In case of respiratory tract irritation, consult a physician. When in doubt or if symptoms are observed, get medical advice.
Symptoms: Cough. May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Take off immediately all contaminated clothing. Wash off any skin contamination immediately.
Symptoms: Erythema (Redness). Oedema.
Rinse immediately carefully and thoroughly with eye-bath or water. Remove contact lenses, if present and easy to do. Continue rinsing. Consult an ophthalmologist. Call a POISON CENTER or doctor/physician.
Symptoms: Irritation Conjunctival redness.
Rinse mouth thoroughly with water. Immediately call a POISON CENTRE/doctor. Never give anything by mouth to an unconscious person or a person with cramps.
Symptoms: Vomiting. Irritation.
Immediate Medical Attention
Upon absorption and metabolism acetonitrile immediately begins a slow release of cyanide, which can continue for several hours. The toxic effects and associated clinical signs of cyanide poisoning may therefore be delayed.
Medical Treatment
If the patient is conscious and breathing normally, administration of oxygen is the only treatment necessary. One ampoule of dicobalt edetate (300 mg) diluted in 20 ml glucose solution is given by slow intravenous injection, being careful to avoid extravasation. Treatment may be repeated if there is an inadequate response to the initial injection.
Firefighting Measures
Extinguishing media, specific hazards, and firefighter protection
ABC-powder, Carbon dioxide (CO2), Dry sand, Nitrogen
In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. Use dry extinguishing powder to extinguish.
Flammable liquids. Risk of ignition. Vapour can form explosive mixtures with air. Causes eye irritation. Vapours can travel considerable distances to a source of ignition where they can ignite, flash back, or explode. Closed containers may burst when pressure and temperature rise.
In case of fire and/or explosion do not breathe fumes. Co-ordinate fire-fighting measures to the fire surroundings.
Firefighter Protection
Wear a self-contained breathing apparatus and chemical protective clothing. Use water spray jet to protect personnel and to cool endangered containers.
Accidental Release Measures
Spill cleanup procedures, containment, and environmental protection
Wear personal protection equipment (refer to section 8). Avoid contact with eyes and skin. Avoid breathing dust/mist. Provide adequate ventilation. Keep away from sources of heat (e.g. hot surfaces), sparks and open flames. Remove victim out of the danger area.
Absorb with liquid-binding material (sand, diatomaceous earth, acid- or universal binding agents).
Take up mechanically.
Cover drains. Do not allow to enter into surface water or drains. Collect contaminated fire extinguishing water separately.
Clear spills immediately. Collect in closed and suitable containers for disposal.
Materials: sand, diatomaceous earth, acid- or universal binding agents
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Handling and Storage
Safe handling precautions, storage conditions, and workplace requirements
Use personal protective equipment as required. Use only in well-ventilated areas. Avoid breathing vapours. Avoid contact with eyes and skin.
Keep container tightly closed and in a well-ventilated place. Keep away from sources of heat (e.g. hot surfaces), sparks and open flames. Protect from sunlight.
Wash hands before breaks and after work. Avoid contact with eyes and skin. When using do not eat, drink or smoke. Provide eye shower and label its location conspicuously.
Usual measures for fire prevention. Have fire-extinguishers in readiness before opening containers. Take precautionary measures against static discharges.
Exposure Controls / PPE
Occupational exposure limits, engineering controls, and protective equipment
Technical measures and the application of suitable work processes have priority over personal protection equipment. If handled uncovered, arrangements with local exhaust ventilation have to be used.
When handling with chemical substances, protective gloves must be worn with the CE-label including the four control digits. Recommended glove articles DIN-/EN-Norms EN ISO 374. In the case of wanting to use the gloves again, clean them before taking off and air them well. By short-term hand contact: Suitable material: NBR (Nitrile rubber), Thickness of the glove material: 0,425 mm, Breakthrough time: 14 min, Recommended glove articles: VWR 112-0971. By long-term hand contact: Suitable material: Butyl caoutchouc (butyl rubber), Thickness of the glove material: 0,30 mm, Breakthrough time: >480 min, Recommended glove articles: VWR 112-3779
Eye glasses with side protection DIN-/EN-Norms EN 166. Recommendation: VWR 111-0432
Respiratory protection necessary at: aerosol or mist formation. Suitable respiratory protection apparatus: Full-/half-/quarter-face masks (EN 136/140). Recommendation: VWR 111-0206. Suitable material: ABEK2P3. Recommendation: VWR 111-0059
Wear suitable protective clothing. When handling with chemical substances, protective clothing with CE-labels including the four control digits must be worn.
no data available
Physical and Chemical Properties
Appearance, physical state, melting point, boiling point, and material characteristics
Stability and Reactivity
Chemical stability, hazardous reactions, and incompatible materials
The product is chemically stable under standard ambient conditions (room temperature).
Vapour can form explosive mixtures with air. Risk of ignition. In case of warming: Risk of ignition.
Violent reaction with: Oxidising agent, Reducing agent, Acid, Alkali metals, Peroxides
This material is combustible and can be ignited by heat, sparks, flames, or other sources of ignition (e.g. static electricity, pilot lights, or mechanical/electrical equipment). Avoid high temperatures or direct sunlight.
Rubber articles, Plastic articles
Decomposition products in case of fire: see section 5.
Ecological Information
Environmental toxicity, biodegradation, and bioaccumulation data
The data for this section has not been processed yet.
Disposal Considerations
Waste treatment methods, disposal recommendations, and waste codes
The data for this section has not been processed yet.
Transport Information
UN numbers, shipping names, transport classes, and regulatory requirements
- UN Number
- 1648
- Shipping Name
- ACETONITRILE
- Transport Class
- 3
- Packing Group
- II
Hazard identification number (Kemler No.): 33 Tunnel restriction code: D/E (Passage forbidden through tunnels of category D when carried in bulk or in tanks. Passage forbidden through tunnels of category E.)
Segregation group: -
Regulatory Information
Chemical regulations, safety assessments, and compliance status
The data for this section has not been processed yet.
Frequently Asked Questions
Common questions about safety, handling, and properties
What other names is Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments known by?
Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments is also known as: Cyanomethane, Ethanenitrile, Ethanoic acid nitrile, Methyl cyanide
What is the hazard signal word for Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments?
The signal word is danger.
What is the physical form of Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments?
Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments is a liquid with colourless color. It has ether-like odor.
What is Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments used for?
General chemical reagent
What are the hazard statements for Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments?
This substance has 3 hazard statements:
- H225: Highly flammable liquid and vapour.
- H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
- H319: Causes serious eye irritation.
What is the melting point of Acetonitrile HiPerSolv CHROMANORM® for HPLC LC-MS grade - suitable for UPLC/UHPLC instruments?
The melting point is -45.7 °C and the boiling point is 81.6 °C (1013 hPa).