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Safety Data Sheet EN

Tetrahydrofuran

CAS 109-99-9
EC 203-726-8

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01

Identification

Product identifiers, regulatory numbers, and supplier information

Product Information

Product Name
Tetrahydrofuran
Product Code
176630000; 176630010; 176630025; 176630050; 176630100; 176630250
Chemical Name
Tetrahydrofuran
Synonyms
THF

Regulatory Identifiers

CAS Number
109-99-9 Check regulations →
EC Number
203-726-8 Check regulations →
REACH No.
01-2119444314-46-0079

Identified Uses

Laboratory chemicals. See Annex for full list. Sector of use: SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites, SU22 - Professional uses: Public domain (administration, education, entertainment, services, craftsmen). Product category: PC21 - Laboratory chemicals. Process categories: PROC3, PROC4, PROC5, PROC 8b, PROC9, PROC15.

Uses advised against

Food, drug, pesticide or biocidal product use; Not suitable for concentration or distillation; SU21 - Consumer uses: Private households (= general public = consumers); REACH Annex XVII Restriction - refer to SECTION 15

Manufacturers & Suppliers

T

Thermo Fisher Scientific

manufacturer

Janssen Pharmaceuticalaan 3a, 2440 Geel, Belgium

F

Fisher Scientific UK

manufacturer

Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom

F

Fisher Scientific AG

distributor

Neuhofstrasse 11, CH 4153 Reinach

+41 (0) 56 618 41 11

Emergency Contacts

Emergency Contact

001-800-227-6701

Emergency Contact

+32 14 57 52 11

Emergency Contact

001-201-796-7100

Emergency Contact

+32 14 57 52 99

CHEMTREC

001-800-424-9300

CHEMTREC

001-703-527-3887

Tox Info Suisse

145

24hr

Tox Info Suisse

+41-44 251 51 51

Chemtrec

0800 564 402

24h

Chemtrec

+41-43 508 20 11

02

Hazard Identification

GHS classification, signal word, pictograms, and hazard statements

Classified danger

Hazard Classifications

Flam. Liq. Cat. 2 H225
Acute Tox. Cat. 4 H302
Eye Irrit. Cat. 2 H319
Carc. Cat. 2 H351
STOT SE Cat. 3 H335
STOT SE Cat. 3 H336

GHS Pictograms

GHS02 - Flammable

GHS02

GHS07 - Health hazard

GHS07

GHS08 - Serious health hazard

GHS08

Hazard Statements

H225 Highly flammable liquid and vapor
H302 Harmful if swallowed
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H351 Suspected of causing cancer

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing
P312 Call a POISON CENTER or doctor if you feel unwell

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03

Composition / Information on Ingredients

Chemical components, concentration ranges, and hazardous substance identification

Type mixture
Chemical Name CAS Number Concentration Hazardous
Tetrahydrofuran EC: 203-726-8 109-99-9 99.9% Yes
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl- EC: 204-881-4 128-37-0 0.025% Yes
04

First Aid Measures

Emergency procedures for chemical exposure incidents

Inhalation

Remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.

Skin contact

Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

Ingestion

Do NOT induce vomiting. Call a physician or poison control center immediately.

Immediate Medical Attention

Get medical attention.

Medical Treatment

Treat symptomatically.

05

Firefighting Measures

Extinguishing media, specific hazards, and firefighter protection

Suitable media

Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam. Water mist may be used to cool closed containers.

Unsuitable media

Do not use a solid water stream as it may scatter and spread fire.

Specific hazards

Flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. May form explosive peroxides. Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition.

Instructions

Water mist may be used to cool closed containers. Keep product and empty container away from heat and sources of ignition.

Firefighter Protection

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

06

Accidental Release Measures

Spill cleanup procedures, containment, and environmental protection

Emergency procedures

Keep people away from and upwind of spill/leak.

Environmental

Should not be released into the environment.

Cleanup methods

Soak up with inert absorbent material.

Materials: inert absorbent material

Related Products

Similar products with comparable safety profiles

07

Handling and Storage

Safe handling precautions, storage conditions, and workplace requirements

Handling

Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Wear personal protective equipment/face protection. Avoid ingestion and inhalation. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded. If peroxide formation is suspected, do not open or move container. Handle under an inert atmosphere.

Storage

Store under an inert atmosphere. Shelf life 30 months (Unopened) or Shelf life: 6 months after opening. Containers should be dated when opened. May form explosive peroxides on prolonged storage. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat, sparks and flame. Flammables area.

Hygiene

Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work.

Fire prevention

Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.

08

Exposure Controls / PPE

Occupational exposure limits, engineering controls, and protective equipment

Engineering

Use explosion-proof electrical/ventilating/lighting/equipment. Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source

Hands

Protective gloves. ACR17663. Glove material: Butyl rubber, Breakthrough time: < 25 minutes, Glove thickness: 0.6 mm, EU standard: Level 1 EN 374, Glove comments: Permeation rate 106 μg/cm2/min As tested under EN374-3 Determination of Resistance to Permeation by Chemicals; Neoprene gloves, Breakthrough time: < 15 minutes, Glove thickness: 0.45 mm. Inspect gloves before use. observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) gloves are suitable for the task: Chemical compatibility, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. gloves with care avoiding skin contamination.

Eyes

Goggles (European standard - EN 166)

Respiratory

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly. Large scale/emergency use: Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended Filter type: Organic gases and vapours filter Type A Brown conforming to EN14387. Small scale/Laboratory use: Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141. When RPE is used a face piece Fit Test should be conducted

Skin/Body

Long sleeved clothing.

Environmental

No information available.

09

Physical and Chemical Properties

Appearance, physical state, melting point, boiling point, and material characteristics

Physical State
Liquid
Physical State Data
liquid
State Under Standard Conditions
---
Appearance
Colorless
Colour
---
Colour Intensity
---
Form
---
Odor
Petroleum distillates
Odor Threshold
No data available
Ph
7-8
Melting Point
-108.4 °C / -163.1 °F
Boiling Point
66 °C / 150.8 °F
Flash Point
-21 °C / -5.8 °F
Freezing Point
---
Softening Point
No data available
Solidification Point
---
Cloud Point
---
Crystallisation Point
---
Relative Evaporation Rate
---
Evaporation Rate
>1 (Ether = 1.0) - (Butyl Acetate = 1.0)
Vapor Pressure
170 mbar @ 20 °C
Vapor Density
2.5 (Ether = 1.0)
Relative Density
0.880
Bulk Density
Not applicable
Density
---
Flammability
---
Upper Explosive Limit
12 vol%
Lower Explosive Limit
1.5 vol%
Explosive Limits
---
Auto Ignition Temperature
215 - °C / 419 - °F
Decomposition Temperature
No data available
Solubility
---
Partition Coefficient
Tetrahydrofuran: 0.45, Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-: 5.1
Solubility In Water
Miscible
Solubility In Fat
---
Molecular Weight
72.11
Voc Content
---
Metal Corrosion
---
Dynamic Viscosity
0.456 mPas @ 20°C
Kinematic Viscosity
---
Properties Status
---
10

Stability and Reactivity

Chemical stability, hazardous reactions, and incompatible materials

Stability

Stable under recommended storage conditions. Reacts with air to form peroxides. May form explosive peroxides on prolonged storage. Hygroscopic.

Reactivity

Yes. May form explosive peroxides

Hazardous reactions

Hazardous polymerization may occur. None under normal processing.

Avoid

Incompatible products. Excess heat. Keep away from open flames, hot surfaces and sources of ignition. Exposure to moist air or water.

Incompatible

Strong oxidizing agents. Acids.

Decomposition

Carbon monoxide (CO). Carbon dioxide (CO2). peroxides.

12

Ecological Information

Environmental toxicity, biodegradation, and bioaccumulation data

The data for this section has not been processed yet.

13

Disposal Considerations

Waste treatment methods, disposal recommendations, and waste codes

The data for this section has not been processed yet.

14

Transport Information

UN numbers, shipping names, transport classes, and regulatory requirements

UN Number
UN2056
Shipping Name
TETRAHYDROFURAN
Transport Class
3
Packing Group
II
15

Regulatory Information

Chemical regulations, safety assessments, and compliance status

The data for this section has not been processed yet.

?

Frequently Asked Questions

Common questions about safety, handling, and properties

What other names is Tetrahydrofuran known by?

Tetrahydrofuran is also known as: THF

What is the hazard signal word for Tetrahydrofuran?

The signal word is danger.

What is the physical form of Tetrahydrofuran?

Tetrahydrofuran is a liquid appearing as colorless . It has petroleum distillates odor.

What is Tetrahydrofuran used for?

Laboratory chemicals. See Annex for full list. Sector of use: SU3 - Industrial uses: Uses of substances as such or in preparations at industrial sites, SU22 - Professional uses: Public domain (administration, education, entertainment, services, craftsmen). Product category: PC21 - Laboratory chemicals. Process categories: PROC3, PROC4, PROC5, PROC 8b, PROC9, PROC15.

What are the hazard statements for Tetrahydrofuran?

This substance has 6 hazard statements:

  • H225: Highly flammable liquid and vapor
  • H302: Harmful if swallowed
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation
  • H336: May cause drowsiness or dizziness
  • H351: Suspected of causing cancer

What is the melting point of Tetrahydrofuran?

The melting point is -108.4 °C / -163.1 °F and the boiling point is 66 °C / 150.8 °F.